anti-Human Tumor Necrosis Factor Antikörper für Immunohistochemistry

Recommended Tumor Necrosis Factor Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor (TNF) Antikörper
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • lipopolysaccharide induced TNF factor
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LITAF
  • LOC103694380
  • tnfa
Reaktivität
Human, Maus, Ratte (Rattus)
1380
528
457
229
223
203
202
59
56
44
32
18
15
9
7
6
6
5
4
4
4
4
3
2
2
1
1
1
1
Wirt
Kaninchen
1071
543
138
50
11
10
8
7
5
2
1
Klonalität
Polyklonal
Konjugat
Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
185
95
71
55
49
26
23
22
21
20
19
19
19
19
19
19
18
17
11
11
11
11
11
11
11
11
11
11
11
11
11
11
11
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
828
804
756
466
403
269
206
169
134
120
100
67
48
42
26
26
25
17
15
13
9
9
9
7
6
6
6
5
5
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Hersteller
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Produktnummer ABIN6269443
$ 450.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
8.85804 ABIN153474 IHC (p) IHC ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal 9
8.85804 ABIN5596796 Neut IHC ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 1
8.85804 ABIN2707185 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN3188055 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN1533583 IF IHC ELISA Rabbit IgG AA 141-190 Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN1875123 IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN3188057 IHC WB Mouse IgG1 Anmelden zum Anzeigen Q36 0
8.85804 ABIN3188056 IHC WB Mouse IgG1 Anmelden zum Anzeigen Q34 0
8.85804 ABIN305730 ELISA FACS IHC IHC (fro) IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 52B83 0
8.85804 ABIN959235 IHC IHC (p) Mouse IgG1 Anmelden zum Anzeigen 2C8 0
8.85804 ABIN790510 ELISA IHC IHC (p) WB Mouse IgG1, kappa AA 1-234 Anmelden zum Anzeigen M 1 C4 0
8.85804 ABIN573983 ELISA ELISpot IHC IHC (p) Mouse IgG1, kappa Anmelden zum Anzeigen MAb1 0
8.85804 ABIN1172395 ICC IHC WB Rabbit IgG AA 77-233 Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN2852671 IHC WB Mouse Anmelden zum Anzeigen 0
8.85804 ABIN1846088 IF/ICC IHC Rabbit Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN1104720 IHC IHC (p) Neut WB Rabbit Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN5964851 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN3020863 IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
8.85804 ABIN5589758 ELISA IHC WB Mouse IgG1 Anmelden zum Anzeigen 4E1 0
8.85804 ABIN2470862 IHC ELISA Mouse IgG1 kappa Anmelden zum Anzeigen MAb1 0

General

Antigen Tumor Necrosis Factor (TNF) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(1380), (528), (457), (229), (223), (203), (202), (59), (56), (44), (32), (18), (15), (9), (7), (6), (6), (5), (4), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(1071), (543), (138), (50), (11), (10), (8), (7), (5), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
(185), (95), (71), (55), (49), (26), (23), (22), (21), (20), (19), (19), (19), (19), (19), (19), (18), (17), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(828), (804), (756), (466), (403), (269), (206), (169), (134), (120), (100), (67), (48), (42), (26), (26), (25), (17), (15), (13), (9), (9), (9), (7), (6), (6), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 10 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Tumor Necrosis Factor Antikörper

Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN6269443) Bilder
Spezifität TNFA Antibody detects endogenous levels of total TNFA
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human TNFA
Isotyp IgG
Plasmids, Primers & others

Target Details Tumor Necrosis Factor

Produktdetails anti-Tumor Necrosis Factor Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN6269443) Bilder zurück nach oben
Antigen
Andere Bezeichnung TNFA (TNF Antibody Abstract)
Hintergrund

Description: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line (PubMed:22517918).

Gene: TNF

Molekulargewicht 17/30-35kDa
Gen-ID 7124
UniProt P01375
Pathways NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN6269443) Bilder zurück nach oben
Applikations-hinweise WB 1:500 IHC 1:50-1:200 IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN6269443) Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer PBS,  pH 7.4,50 % glycerol.

Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN6269443)

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Sun, Xu, Yi, Chen, Wu, Cao, Zhou, Jiang, Zhang: "Role of 5-HT1A receptor in insular cortex mediating stress - induced visceral sensory dysfunction." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 28, Issue 7, pp. 1104-13, 2018

Feng, Cui, Liu, Wu, Hu, Zhang, Ma, Wang: "Protective Role of Apocynin via Suppression of Neuronal Autophagy and TLR4/NF-κB Signaling Pathway in a Rat Model of Traumatic Brain Injury." in: Neurochemical research, Vol. 42, Issue 11, pp. 3296-3309, 2018

Hu, Cheng, Huang, Cai, Lian, Wang, Gao: "Effects of Xin-Ji-Er-Kang on heart failure induced by myocardial infarction: Role of inflammation, oxidative stress and endothelial dysfunction." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 42, pp. 245-257, 2018

Sheng, Wang, Guo, Xu, Jiang, Zheng, Xu, Zhang, Che, Liang, Zhu, Li: "Effects of Baicalin on Diabetic Cardiac Autonomic Neuropathy Mediated by the P2Y12 Receptor in Rat Stellate Ganglia." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 3, pp. 986-998, 2018

Zhu, Xu, Lv, He, Ye, Wang, Hu: "miR-199b-5p Regulates Immune-Mediated Allograft Rejection after Lung Transplantation Through the GSK3β and NF-κB Pathways." in: Inflammation, Vol. 41, Issue 4, pp. 1524-1535, 2018

Guo, Sheng, Dan, Xu, Zhang, Ji, Wang, Xu, Che, Li, Liang, Li: "Involvement of P2Y12 receptor of stellate ganglion in diabetic cardiovascular autonomic neuropathy." in: Purinergic signalling, 2018

Yuan, Ouyang, Yang, Li, Gong, Zou, Jia, Zhao, Wu, Yi, Liu, Shi, Li, Gao, Li, Xu, Liu, Zhang, Liang: "Osthole alleviated diabetic neuropathic pain mediated by the P2X4 receptor in dorsal root ganglia." in: Brain research bulletin, Vol. 142, pp. 289-296, 2018

Feng, Gao, Cui, Li, Li, Cui, Cui: "Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway." in: Cellular and molecular neurobiology, Vol. 37, Issue 1, pp. 155-168, 2017

Zhang, Zou, Zhang, Fu, Xu, Wang, Xia, Huang, Gan, Zhu, Xu: "A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation." in: Experimental neurology, Vol. 297, pp. 1-13, 2017

Feng, Cui, Gao, Li, Li, Jiang, Tian, Wang, Cui, Cui: "Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury." in: International journal of molecular medicine, Vol. 37, Issue 4, pp. 921-30, 2016

Bilder

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN6269443) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) Western blot analysis of extracts from COLO cells,using TNFA Antibody.The lane on the...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, usin...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) ABIN6269444 staining A-431 cells by IF/ICC. The sample were fixed with PFA and permea...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN6269443) Western blot analysis of extracts of various celllines,using TNFA antibody.