anti-Human Tumor Necrosis Factor Antikörper für Immunohistochemistry

Recommended Tumor Necrosis Factor Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor (TNF) Antikörper
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LOC103694380
  • tnfa
Reaktivität
Human
1380
530
459
229
223
203
202
59
56
44
32
18
15
9
7
6
6
5
4
4
4
4
3
2
2
1
1
1
1
Wirt
Kaninchen
1071
543
138
52
11
10
8
7
5
2
1
Klonalität
Polyklonal
Konjugat
Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
185
95
71
55
49
26
23
22
21
20
19
19
19
19
19
19
18
17
11
11
11
11
11
11
11
11
11
11
11
11
11
11
11
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Neutralization (Neut), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
830
806
756
468
405
269
206
170
133
120
100
67
48
42
26
26
25
17
15
13
9
9
9
7
6
6
6
5
5
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Optionen
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Bilder

Produktnummer ABIN5596796
$ 583.50
Zzgl. Versandkosten $45.00 und $23.00 Trockeneis
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
29.470049 ABIN6269443 ELISA ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 10
27.549633 ABIN3188055 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
24.549633 ABIN3188056 IHC WB Mouse IgG1 Anmelden zum Anzeigen Q34 0
24.549633 ABIN3020863 IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
21.549633 ABIN3188057 IHC WB Mouse IgG1 Anmelden zum Anzeigen Q36 0
18.970049 ABIN1875123 IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
18.579586 ABIN6149290 IHC WB Rabbit Anmelden zum Anzeigen Polyclonal 0
15.579585 ABIN3187296 ELISA IF IHC Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
13 ABIN6171930 FACS IF IHC APC Mouse IgM, kappa Anmelden zum Anzeigen TNFA-1172 0
13 ABIN6171937 FACS IF IHC PerCP Mouse IgM, kappa Anmelden zum Anzeigen TNFA-1172 0
13 ABIN6171938 FACS IF IHC PE Mouse IgM, kappa Anmelden zum Anzeigen TNFA-1172 0
13 ABIN6171941 FACS IF IHC Mouse IgM, kappa Anmelden zum Anzeigen TNFA-1172 0
12.970049 ABIN790510 ELISA IHC IHC (p) WB Mouse IgG1, kappa AA 1-234 Anmelden zum Anzeigen M 1 C4 0
12.970049 ABIN1172395 ICC IHC WB Rabbit IgG AA 77-233 Anmelden zum Anzeigen Polyclonal 0
12.579585 ABIN5668145 BR ELISA IF IHC Human IgG1, kappa Anmelden zum Anzeigen D2E7 (Adalimumab) 0
12.579585 ABIN5668146 BR ELISA IF IHC Rabbit IgG, kappa Anmelden zum Anzeigen Chimeric 0
12.579585 ABIN5620992 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
12.579585 ABIN284915 Inhibition IHC ELISA Mouse IgG1 Anmelden zum Anzeigen M32253 0
12.579585 ABIN284821 Inhibition IHC ELISA Mouse IgG1 Anmelden zum Anzeigen 1D9 0
12.579585 ABIN284916 IHC ELISA Mouse IgG1 Anmelden zum Anzeigen M32255 0

General

Antigen Tumor Necrosis Factor (TNF) Antikörper
Reaktivität Human
(1380), (530), (459), (229), (223), (203), (202), (59), (56), (44), (32), (18), (15), (9), (7), (6), (6), (5), (4), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(1071), (543), (138), (52), (11), (10), (8), (7), (5), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
(185), (95), (71), (55), (49), (26), (23), (22), (21), (20), (19), (19), (19), (19), (19), (19), (18), (17), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Neutralization (Neut), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(830), (806), (756), (468), (405), (269), (206), (170), (133), (120), (100), (67), (48), (42), (26), (26), (25), (17), (15), (13), (9), (9), (9), (7), (6), (6), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Tumor Necrosis Factor Antikörper

Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN5596796) Bilder
Spezifität This antibody is primarily directed against mature 17,000 MW human TNFalpha and is useful in determining its presence in various assays. In general, this antibody also detects primate TNFalpha in the same formats using similar dilutions. The antibody does not recognize human TNGß (lymphotoxin). This IgG fraction antibody will recognize the cell-bound precursor of TNFalpha as a 26,000 protein in immunoblots, particularly in denatured samples. This antibody is also useful for neutralization of human and primate TNFalpha activity in bioassays. It does not neutralize the biological activity of lymphotoxin. For neutralization, it is recommended to incubate the sample with a 1:200 dilution of the antibody for at least 4 hours before being tested. A control of similarly diluted normal rabbit IgG is recommended.
Produktmerkmale Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-alpha) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNFis an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD).
Sterilität Sterile filtered
Immunogen The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human TNFalpha produced in E.coli.
Immunogen Type: RecombinantProtein
Isotyp IgG
Plasmids, Primers & others

Target Details Tumor Necrosis Factor

Produktdetails anti-Tumor Necrosis Factor Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN5596796) Bilder zurück nach oben
Antigen
Andere Bezeichnung TNF alpha (TNF Antibody Abstract)
Hintergrund Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-α) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNFis an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD).
Synonyms: APC1 antibody, Cachectin antibody, DIF antibody, Differentiation inducing factor antibody, Macrophage cytotoxic factor antibody, MCF antibody, Necrosin antibody
Gen-ID 7124
UniProt P01375
Pathways NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN5596796) Bilder zurück nach oben
Applikations-hinweise This IgG fraction antibody of anti-Human TNFα has been tested for use in neutralizations, ELISA, immunohistochemistry and immunoblotting. It recognizes the 17,000 MW TNFα. Reactivity in other immunoassays is unknown.
Kommentare

Gene Name: TNFA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN5596796) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Konservierungs-mittel Without preservative
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Haltbarkeit 12 months

Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN5596796)

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Kant, Swat, Zhang, Zhang, Neel, Flavell, Davis: "TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway." in: Genes & development, Vol. 25, Issue 19, pp. 2069-78, 2011

Bilder

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN5596796) zurück nach oben
Bilder des Herstellers
 image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) anti-Tumor Necrosis Factor (TNF) antibody
 image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) anti-Tumor Necrosis Factor (TNF) antibody (Image 2)
Immunofluorescence (IF) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Fluorescent immunohistochemistry showing staining of human colon by anti-TNF alpha (...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Western blot of Anti-Human TNF-a (RABBIT) Antibody. Lane 1: 250ng human recombinant T...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Western Blot of Rabbit anti-TNF Alpha antibody. Marker: Opal Pre-stained ladder . Lan...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Western blot using Anti-Human TNF-a (RABBIT) Antibody. Membrane blocked in 1% BSA-TB...
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN5596796) Immunohistochemistry using polyclonal TNFa antibody showing staining of formalin/PFA...