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Protein Phosphatase 4, Regulatory Subunit 2 Produkte

(Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

Kategorien

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair (By similarity). Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage- dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).

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Ausgewählte Protein Phosphatase 4, Regulatory Subunit 2 Kategorien

Protein Phosphatase 4, Regulatory Subunit 2 Antikörper

High quality antibodies with extensive validation data.

Protein Phosphatase 4, Regulatory Subunit 2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Protein Phosphatase 4, Regulatory Subunit 2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7075284
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, ICC
Validierungen
  • (2)
Kat. Nr. ABIN6257426
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN1500387
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Protein Phosphatase 4, Regulatory Subunit 2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6206801
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Protein Phosphatase 4, Regulatory Subunit 2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094683
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3134898
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Rabbit
Source Yeast
Validierungen
Kat. Nr. ABIN1473073
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Protein Phosphatase 4, Regulatory Subunit 2 Produkten

Bosio, Berto, Camera, Bianchi, Ambrogio, Claus, Di Cunto: "PPP4R2 regulates neuronal cell differentiation and survival, functionally cooperating with SMN." in: European journal of cell biology, Vol. 91, Issue 8, pp. 662-74, (2012) (PubMed).

Goudreault, DAmbrosio, Kean, Mullin, Larsen, Sanchez, Chaudhry, Chen, Sicheri, Nesvizhskii, Aebersold, Raught, Gingras: "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 157-71, (2009) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Synonyme und alternative Namen zu Protein Phosphatase 4, Regulatory Subunit 2

protein phosphatase 4 regulatory subunit 2 (PPP4R2), protein phosphatase 4, regulatory subunit 2 (Ppp4r2), protein phosphatase 4, regulatory subunit 2a (ppp4r2a), protein phosphatase 4 regulatory subunit 2 S homeolog (ppp4r2.S), protein phosphatase 4 regulatory subunit 2 (ppp4r2), protein phosphatase 4 regulatory subunit 2 L homeolog (ppp4r2.L), protein phosphatase 4, regulatory subunit 2b (ppp4r2b), BE691708, C230060M08Rik, fe11b04, PP4R2, ppp4r2, ppp4r2-B, wu:fa17h08, wu:fc23g05, wu:fe11b04

Bezeichner auf Proteinebene für Protein Phosphatase 4, Regulatory Subunit 2

  • serine/threonine-protein phosphatase 4 regulatory subunit 2
  • serine/threonine-protein phosphatase 4 regulatory subunit 2-A
  • protein phosphatase 4, regulatory subunit 2
  • serine/threonine-protein phosphatase 4 regulatory subunit 2-B
  • Serine/threonine-protein phosphatase 4 regulatory subunit 2
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