anti-PEPCK (PEPCK) Antikörper

Bezeichnung:: anti-phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) Antikörper (PEPCK)

Auf www.antikoerper-online.de finden Sie aktuell 92 phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Antikörper von 0 unterschiedlichen Herstellern. Insgesamt sind aktuell 123 PEPCK Produkte verfügbar.

Synonyme:: 1810010O14Rik, 9130022B02Rik, id:ibd5157, pck, pck2, pck2.S, PEPCK, PEPCK-M, PEPCK2, zgc:77867

Alle Antikörper anzeigen	Gen	GeneID	UniProt
Anti-Human PEPCK	PEPCK	5106	Q16822
Anti-Maus PEPCK	PEPCK	74551	Q8BH04
Anti-Ratte PEPCK	PEPCK	361042
Weitere Synonyme anzeigen

Verknüpfte Pathways mit anti-PEPCK Antikörper

Weitere Produktkategorien zu PEPCK Antikörper

Am meisten referenzierte anti-PEPCK Antikörper

Guinea Pig Polyclonal PEPCK Primary Antibody für ELISA, WB - ABIN250823 : Zhou, Li, Qi, Zhang, Zhang, Wu, Hu, Wu, Liu, Yan, Jing, Liu, Zhai: Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity. in Diabetologia 2012 (PubMed)
Show all 2 Pubmed References
Green bean (Phaseolus vulgaris) Polyclonal PEPCK Primary Antibody für WB - ABIN249350 : Aragón, Pascual, González, Escalona, Carvalho, Amancio: The physiology of ex vitro pineapple (Ananas comosus L. Merr. var MD-2) as CAM or C3 is regulated by the environmental conditions: proteomic and transcriptomic profiles. in Plant cell reports 2013 (PubMed)
Human Polyclonal PEPCK Primary Antibody für ELISA, WB - ABIN185483 : Duplus, Benelli, Reis, Fouque, Velho, Forest: Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue: induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes. in Biochimie 2004 (PubMed)
Show all 2 Pubmed References

Weitere Antikörper gegen PEPCK Interaktionspartner

Human phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Interaktionspartner

Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma
ApoA-IV (zeige APOA4 Antikörper) colocalizes with NR4A1 (zeige NR4A1 Antikörper), which suppresses G6Pase (zeige G6PC Antikörper) and PEPCK gene expression at the transcriptional level, reducing hepatic glucose output and lowering blood glucose.
Results indicate that PEPCK promotes tumor growth by increasing glucose and glutamine (zeige GFPT1 Antikörper) metabolism, increases anabolic metabolism and promotes mTORC1 activity.
Mitochondrial PCK2 regulates metabolic adaptation and enables glucose-independent tumor growth in various neoplasms.
When autophagy was blocked, the level of glucose-6-phosphatase (G6Pase (zeige G6PC Antikörper)) and phosphoenolpyruvate carboxykinase (PEPCK) was reduced in HepG2 cells and not in Hep3B cells.
PEPCK activity was elevated threefold in lung cancer samples over normal lungs and its activation mediates an adaptive response to glucose depletion in lung cancer.
Amino acid limitation and ER stress inducers, conditions that activate the amino acid response (AAR) and the unfolded protein response (UPR), stimulate PCK2 gene transcription in tumor cell lines.
Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells.
expression of HCV nonstructural component NS5A in Huh7 or primary hepatocytes stimulated PEPCK gene expression and glucose output in HepG2 cells.
results reveal a novel link between glucose metabolism and the DNA damage signaling pathway and suggest a possible role for PEPCK and G6P in the DNA damage response

Mouse (Murine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Interaktionspartner

Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma
Lactate maintains/induces populations of postnatal neuronal progenitors/neural stem cells in a PEPCK-M-dependent manner
Amino acid limitation and ER stress inducers, conditions that activate the amino acid response (AAR) and the unfolded protein response (UPR), stimulate PCK2 gene transcription in tumor cell lines.
PEPCK-M expression partially rescued defects in lipid metabolism, gluconeogenesis and TCA cycle function impaired by PEPCK-C deletion, while approximately 10% re-expression of PEPCK-C normalized most parameters.
Data show that PEPCK-M message and protein were detected in islets.

Cow (Bovine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Interaktionspartner

Transition to lactation does not alter expression of the mitochondrial form of PEPCK.

Pig (Porcine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Interaktionspartner

Concurrent binding and modifications of AUF1 (zeige HNRNPD Antikörper) and HuR (zeige ELAVL1 Antikörper) mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells.

PEPCK Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with PEPCK

phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2) Antikörper
phosphoenolpyruvate carboxykinase 2 (mitochondrial) (Pck2) Antikörper
phosphoenolpyruvate carboxykinase 2 (mitochondrial) (pck2) Antikörper
phosphoenolpyruvate carboxykinase 2, mitochondrial (Pck2) Antikörper
phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog (pck2.L) Antikörper

1810010O14Rik Antikörper
9130022B02Rik Antikörper
id:ibd5157 Antikörper
pck Antikörper
pck2 Antikörper
pck2.S Antikörper
PEPCK Antikörper
PEPCK-M Antikörper
PEPCK2 Antikörper
zgc:77867 Antikörper

Bezeichner auf Proteinebene für PEPCK

PEP carboxykinase , phosphoenolpyruvate carboxykinase [GTP], mitochondrial , phosphoenolpyruvate carboxylase , phosphopyruvate carboxylase , mitochondrial phosphoenolpyruvate carboxykinase 2 , phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog , phosphoenolpyruvate carboxykinase 2 (mitochondrial) S homeolog

GENE ID	SPEZIES
5106	Homo sapiens
74551	Mus musculus
282856	Bos taurus
361042	Rattus norvegicus
396457	Gallus gallus
406473	Danio rerio
452807	Pan troglodytes
480255	Canis lupus familiaris
100054903	Equus caballus
403165	Sus scrofa
100715252	Cavia porcellus
399424	Xenopus laevis

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Show all anti-phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Antikörper with Pubmed References