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Human Polyclonal CCKBR Primary Antibody für IHC, ELISA - ABIN185407
Olszewska-Pazdrak, Townsend, Hellmich: Agonist-independent activation of Src tyrosine kinase by a cholecystokinin-2 (CCK2) receptor splice variant. in The Journal of biological chemistry 2004
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Human Polyclonal CCKBR Primary Antibody für IF (p), IHC (p) - ABIN734318
Mohammad, Ozaki, Takeuchi, Unno, Yamoto, Morioka, Takiguchi, Ikeda: Functional compensation between cholecystokinin-1 and -2 receptors in murine paraventricular nucleus neurons. in The Journal of biological chemistry 2012
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Human Polyclonal CCKBR Primary Antibody für ICC, IF - ABIN251249
Berna, Seiz, Nast, Benten, Bläker, Koch, Lohse, Pace: CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production. in The Journal of biological chemistry 2010
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Cow (Bovine) Polyclonal CCKBR Primary Antibody für EIA, IHC (p) - ABIN372564
El-Kouhen, Morisset: Cholecystokinin and Somatostatin Negatively Affect Growth of the Somatostatin-RIN-14B Cells. in International journal of endocrinology 2009
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High CCK2R expression is associated with cancer.
These results suggest that Z-360 exerts an anti-tumor effect through a reduction in anti-apoptosis factors by blocking CCK2R
High CCK-BR expression is associated with Gastric Cancer.
There is no identifiable link between nuclear CCK2R expression and all the clinicopathological characteristics examined in a cohort of Taiwanese colon cancer patients.
Our study showed significantly higher expression of CCKAR (zeige CCKAR Antikörper) and down regulation of CCKBR in pancreatic cancer as compared to control while CCKBR/GR was detected in majority of stomach cancer samples. Thus, our study suggests that CCK (zeige CCK Antikörper) and Gs receptors may have diagnostic and therapeutic implications.
Data indicate that variant c.811+32C>A in cholecystokinin-B receptor gene (CCKBR) does not have a significant impact on pancreatic cancer risk or survival in a Hungarian cohort.
The neurotransmitter cholecystokinin (CCK (zeige CCK Antikörper)), along with its receptors, CCKAR (zeige CCKAR Antikörper) and CCKBR, have been previously associated with psychiatric disorders, suggesting that variants near these genes may play a role in the pre-pulse/startle response in this cohort
There is functional synergy between cholecystokinin (zeige CCK Antikörper) receptors CCKAR (zeige CCKAR Antikörper) and CCKBR in mammalian brain development.
CCK-BR SNP predicts survival and should be studied as a candidate genetic biomarker for those at risk of pancreatic cancer.
treatment with gastrin (zeige GAST Antikörper), a CCK2R agonist, stimulated the secretion of GLP-1 (zeige GCG Antikörper), and that this effect was likely due to increased expression of proglucagon (zeige GCG Antikörper) and PCSK1 (zeige PCSK1 Antikörper) (also known as prohormone convertase 3 (PC3 (zeige PCSK1 Antikörper) gene)).
Our data suggest a progression model for BE to EAC (zeige CYLD Antikörper) in which CCK2R+ progenitor cells, stimulated by hypergastrinemia, proliferate to give rise to metaplasia and dysplasia.
CCKBR and D5R synergistically interact in the kidney, which may contribute to the maintenance of normal sodium balance following an increase in sodium intake
findings provide novel evidence that Cnr1 (zeige CNR1 Antikörper) contributes to cued fear expression via an interaction with the CCKB receptor.
mice lacking CCK (zeige CCK Antikörper) receptors exhibited a functional shift from the gastrin (zeige GAST Antikörper)-CCK (zeige CCK Antikörper) pathways to the neuronal pathway in control of the ECL (zeige APOC4 Antikörper) cells and eventually the acid secretion
CCK2R labels +4 antral stem cells that can be activated and expanded by progastrin, thus identifying one hormonal trigger for gastric stem cell interconversion and a potential target for gastric cancer chemoprevention and therapy.
CCK-1 (zeige CCL28 Antikörper) and -2 receptors may function synergistically in single PaPo neurons and deletion of CCK-1 (zeige CCL28 Antikörper) receptors may facilitate CCK (zeige CCK Antikörper)-2 receptor signaling.
cholecystokinin receptor-2 has a role in stress-triggered fear memory and anxiety in the mouse
shift of breakpoint on Arrhenius plot established in CCK (zeige CCK Antikörper)(2) receptor-deficiency confirms that such kind of alteration in Na(+),K(+)-ATPase (zeige ATP1A1 Antikörper) temperature dependence is likely related to the homeostatic adjustment of altered function of the sodium pump.
Environmental enrichment has beneficial effects in neuropathic conditions and reinforce the causal link between CCK(2) receptors, mechanical sensitivity and the development of CCI-induced hypersensitivity.
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
cholecystokinin B receptor
, gastrin/cholecystokinin type B receptor
, CCK-B receptor
, CCK2 receptor
, cholecystokinin-2 receptor
, gastrin receptor
, CCK(B) receptor
, CCK-B/gastrin receptor
, CCK2/gastrin receptor
, Cholecystokinin-2 receptor
, gastrin/CCK-B receptor
, cholecystokinin receptor