Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human SOX7 Antikörper:
anti-Mouse (Murine) SOX7 Antikörper:
anti-Rat (Rattus) SOX7 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Monoclonal SOX7 Primary Antibody für BI, IF - ABIN2689906
Costa, Mazan, Gandillet, Pearson, Lacaud, Kouskoff: SOX7 regulates the expression of VE-cadherin in the haemogenic endothelium at the onset of haematopoietic development. in Development (Cambridge, England) 2012
Show all 3 Pubmed References
Human Polyclonal SOX7 Primary Antibody für IHC, IHC (p) - ABIN4355421
Saegusa, Hashimura, Kuwata: Sox4 functions as a positive regulator of β-catenin signaling through upregulation of TCF4 during morular differentiation of endometrial carcinomas. in Laboratory investigation; a journal of technical methods and pathology 2012
Show all 2 Pubmed References
SOX7 inhibits oncogenic beta-catenin (zeige CTNNB1 Antikörper)-mediated transcription by disrupting the beta-catenin (zeige CTNNB1 Antikörper)/BCL9 (zeige BCL9 Antikörper) interaction.
Overexpression of miR (zeige MLXIP Antikörper)-935 inhibited SOX7 expression.
The results suggest that miR (zeige MLXIP Antikörper)-664 functions as an oncogene (zeige RAB1A Antikörper) miRNA and has an important role in promoting human osteosarcoma cell invasion and migration by suppressing SOX7 expression.
miR (zeige MLXIP Antikörper)-595 played a critical role in carcinogenesis by suppression of SOX7.
Aberrant methylation of the promoter regions of the SOX7 gene in patients with acute myeloid leukemias.
miR (zeige MLXIP Antikörper)-935 contributed to cell proliferation of gastric cancer through targeting SOX7.
the HMG (zeige SSRP1 Antikörper)-box is a key domain of SOX7 for negatively regulating the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling pathway when functioning as a tumor suppressor in a glioma.
The results provided unequivocal evidence for a novel tumor suppressor role of SOX7 in acute myeloid leukemia (zeige BCL11A Antikörper)
SOX7 plays an important inhibitory role in hepatocarcinogenesis, and might be a novel target for hepatocellular carcinoma therapy.
Ectopic expression of miR (zeige MLXIP Antikörper)-492 led to downregulation of SOX7 protein.
Data provide evidence that the uncontrolled expression of the transcription factor SOX7 in adult haematopoietic cells has dramatic consequences on blood homeostasis with alterations of the haematopoietic system, inducing the proliferation of blood progenitors in the bone marrow while blocking B lymphopoiesis.
SOX7 inhibits the expression of RUNX1 (zeige RUNX1 Antikörper) target genes in hemogenic endothelium, while having no effect on RUNX1 (zeige RUNX1 Antikörper) expression itself. SOX7 directly interacts with RUNX1 (zeige RUNX1 Antikörper) and inhibits its transcriptional activity.
Dynamically and epigenetically coordinated GATA2 (zeige GATA2 Antikörper)/ETS1SOX7 transcription factor expression is indispensable for endothelial cell differentiation.
combined deletion of Sox7, Sox17 (zeige SOX17 Antikörper), and Sox18 (zeige SOX18 Antikörper) at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 (zeige SOX17 Antikörper) allele largely restores arterial identity
These data indicate that Sox7 is dispensable for both differentiation and maturation of primitive endoderm in an mouse embryonic stem cell model system.
ETV2 (zeige ETV2 Antikörper) directly regulates Sox7, and ETV2 (zeige ETV2 Antikörper) governs endothelial development by regulating transcriptional networks which include Sox7.
Notch and SoxF factors combinatorially regulate Dll4 expression in arteries downstream of VEGF.
Haploinsufficiency of Sox7 or Gata4 (zeige GATA4 Antikörper) is sufficient to produce anterior congenital diaphragmatic hernia in mice.
SOX7 regulates the expression of VE-cadherin (zeige CDH5 Antikörper) in the haemogenic endothelium at the onset of haematopoietic development.
Sox7-sustained expression in the earliest committed hematopoietic precursors promotes the maintenance of their multipotent and self-renewing status.
Sox7 levels are crucial in arterial specification in conjunction with hey2 (zeige HEY2 Antikörper) and efnb2 (zeige EFNB2 Antikörper) function, with mutants in all three genes displaying shunt formation and an arterial block.
Sox7/18 factors and Notch (zeige NOTCH1 Antikörper) regulate nr2f2 (zeige NR2F2 Antikörper) gene expression during venous differentiation in zebrafish.
Sox7 and Sox18 (zeige SOX18 Antikörper)-mediated transcriptional regulation of Robo4 (zeige ROBO4 Antikörper) is important in the developing embryonic vasculature
Sox7 and sox18 (zeige SOX18 Antikörper) are specifically expressed in the developing vasculature, and simultaneous loss of their function results in a severe loss of the arterial identity of the presumptive aorta.
Sox7 and sox18 (zeige SOX18 Antikörper) play redundant but collectively essential roles in the establishment of proper arteriovenous identity in zebrafish.
Sox7 and Sox18 (zeige SOX18 Antikörper) control arterial-venous identity by regulating Gridlock (zeige HEY2 Antikörper) expression.
SOX7 mRNA is localized to the vegetal region of the blastula-stage embryo
SOX7 and SOX18b are essential regulators of cardiogenesis in Xenopus.
Vegetal pole localized Sox7 positively regulates Nodal (Xnr4, Xnr5, and Xnr6) expression, as well as the expression of genes involved in mesodermal (Xmenf, Slug, and Snail) and endodermal (Endodermin and Sox17beta) differentiation.
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.
transcription factor SOX-7
, SRY-box containing gene 7
, SRY (sex determining region Y)-box 7
, SRY (sex determining region Y)-box 7, xSox7 protein
, transcription factor Sox-7