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Human Polyclonal RPS3 Primary Antibody für ELISA, ICC - ABIN1169439
Kim, Jang, Kim, Lee, Ahn, Kim: Interaction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradation. in Molecular biology of the cell 2006
Show all 2 Pubmed References
Results found that BfrB subverts the host innate immune system by binding the NF-kappaB (zeige NFKB1 Antikörper) subunit RPS3 and promotes the survival of mycobacteria in macrophages by inhibiting cytokine production in host cells.
These results reveal that RPS3 upregulates XIAP (zeige XIAP Antikörper) independently of the NF-kappaB (zeige NFKB1 Antikörper) pathway in human breast cancer cells
Asn 165 residue of rpS3 is a critical site for N-linked glycosylation and passage through the ER-Golgi secretion pathway.
Short 5'UTR (zeige UTS2R Antikörper) mRNAs are enriched with TISU (translation initiator of short 5'UTR (zeige UTS2R Antikörper)), a 12-nucleotide element directing efficient scanning-independent translation. This study demonstrate that TISU is particularly dependent on eukaryotic initiation factor (zeige EIF4G1 Antikörper) 1A (eIF1A (zeige EIF1AX Antikörper)) which interacts with both RPS3 and RPS10e.
Data show that ribosomal protein S3 (RPS3) knockdown decreased mitochondrial calcium uptake 1 (zeige MICU1 Antikörper) protein (MICU1 (zeige MICU1 Antikörper)) expression.
a novel cell fate determination mechanism to ensure cells undergo programed cell death through interfering with RPS3/NF-kappaB (zeige NFKB1 Antikörper)-conferred anti-apoptotic transcription by the fragment from partial p65 (zeige GORASP1 Antikörper) cleavage by activated Caspase-3 (zeige CASP3 Antikörper)
Increased RPS3 expression is associated with osteosarcoma invasion.
RPS3, a component of basic translation machinery operates at initiation and most probably elongation of protein synthesis, is also implicated in various events of the cell life as an extraribosomal player. [Review]
IkappaBalpha (zeige NFKBIA Antikörper) sequesters not only p65 (zeige GORASP1 Antikörper) but also RPS3 in the cytoplasm.
These findings suggest that the secreted rpS3 protein is an indicator of malignant tumors.
The RPS3 gene silencing ameliorates experimental asthma, probably by disrupting NF-kappaB (zeige NFKB1 Antikörper) activity. RPS3 could be a novel therapeutic target for allergic airway inflammation.
a novel cell fate determination mechanism to ensure cells undergo programed cell death through interfering with RPS3/NF-kappaB (zeige NFKB1 Antikörper)-conferred anti-apoptotic transcription by the fragment from partial p65 (zeige NFkBP65 Antikörper) cleavage by activated Caspase-3 (zeige CASP3 Antikörper)
Rps3 knockdown increased the radiation sensitivity of FDC-P1, confirming that the mechanism of action of Lxn (zeige LXN Antikörper) is mediated by Rps3 pathway.
RpS3 is expressed only in activated microglia after lipopolysaccharide treatment; strong rpS3 immunoreactivity is shown in non-pyramidal and non-granule cells.
oxidative stress regulates the phosphorylation status of nonribosomal rpS3 by both activating PKCdelta (zeige PKCd Antikörper) and blocking the PP2A (zeige PPP2R2B Antikörper) interaction with rpS3
dOgg1 and RpS3 in mitochondria increase cell survival after exposure to the nitric oxide donor SNAP
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
40S ribosomal protein S3
, IMR-90 ribosomal protein S3
, 40S ribosomal protein S3-A
, ribosomal protein S3
, rps3 gene
, 40S ribosomal protein S3-B
, ribosomal protein S3B