anti-Ratte (Rattus) Transportin 1 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Transportin 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Transportin 1 (TNPO1) Antikörper
  • IPO2
  • KPNB2
  • MIP
  • MIP1
  • TRN
  • TNPO1
  • AU021749
  • D13Ertd688e
  • Kpnb2
  • ATTRN1
  • F12A24.13
  • F12A24_13
  • TRANSPORTIN 1
  • transportin 1
  • DKFZp469O204
  • Mip1
  • Znf667
  • mip1
  • zgc:100858
  • transportin 1
  • transportin-1
  • transportin 1 S homeolog
  • zinc finger protein 667
  • major intrinsic protein of lens fiber a
  • TNPO1
  • LOC738932
  • tnpo1
  • Tnpo1
  • tnpo1.S
  • TRN1
  • Zfp667
  • mipa
Epitop
Center
16
14
5
5
5
5
4
2
2
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
88
36
30
27
25
25
21
2
1
1
1
Wirt
Kaninchen
69
29
3
Klonalität
Polyklonal
Konjugat
Dieser Transportin 1 Antikörper ist unkonjugiert
7
7
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
78
40
40
38
31
13
12
6
6
3
2
2
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5554992
$ 469.32
Zzgl. Versandkosten $45.00
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General

Antigen Transportin 1 (TNPO1) Antikörper
Epitop Center
(16), (14), (5), (5), (5), (5), (4), (2), (2), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(88), (36), (30), (27), (25), (25), (21), (2), (1), (1), (1)
Wirt Kaninchen
(69), (29), (3)
Klonalität
Polyklonal
Konjugat Dieser Transportin 1 Antikörper ist unkonjugiert
(7), (7), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(78), (40), (40), (38), (31), (13), (12), (6), (6), (3), (2), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Transportin 1 Antikörper

Target Details Transportin 1 Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects MIP1 at center.
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse, rat
Reinigung Peptide affinity chromatography
Immunogen MAPKAP1 antibody was raised against a 18 amino acid peptide from near the center of human MAPKAP1.
Isotyp IgG

Target Details Transportin 1

Produktdetails anti-Transportin 1 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung MIP1 (TNPO1 Antibody Abstract)
Hintergrund MAPKAP1 was initially identified as the human homolog of S. pombe SIN1. Recent evidence has shown that it identical to Mip1, a protein that interacts with MEKK2, a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network. MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2, thereby blocking the JNK1/2, ERK1/2, p38 and ERK5 MAPKs. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Experiments showed that MAPKAP1 helped to maintain the TOR/rictor assembly but not the TOR/RAPTOR complex, which allowed specific phosphorylation of Akt, a kinase that is believed to couple the growth factor-PI3K signaling pathway to the nutrient-regulated TOR signaling pathway. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.Synonyms: MAPKAP1, Mitogen-activated protein kinase 2-associated protein 1, SAPK-interacting protein 1, SIN1, Stress-activated map kinase-interacting protein 1, TORC2 subunit MAPKAP1, Target of rapamycin complex 2 subunit MAPKAP1, mSIN1
Gen-ID 79109
NCBI Accession NP_001006618
UniProt Q9BPZ7
Pathways PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-Transportin 1 Antikörper Target Details Transportin 1 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Transportin 1 Antikörper Target Details Transportin 1 Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.