anti-Ratte (Rattus) PDPK1 Antikörper für Intracellular Staining

Recommended PDPK1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antikörper
  • pdpk1
  • MGC82080
  • PDK1
  • PDPK2
  • PRO0461
  • Pdk1
  • ATP5A
  • si:zfos-979f1.3
  • 1210
  • BG02759
  • CG1201
  • CG1210
  • DSTPK61
  • Dmel\\CG1210
  • Dstpk61
  • PDK
  • PDK-1
  • PDK1/Pk61C
  • PK61C
  • Pk61C
  • Pk61C/PDK1
  • dPDK-1
  • dPDK1
  • dSTPK61
  • pk61c
  • 3'-phosphoinositide-dependent protein kinase 1
  • 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1
  • ATPDK1
  • AtPDK1
  • T32M21.110
  • T32M21_110
  • 3-phosphoinositide dependent protein kinase 1
  • 3-phosphoinositide dependent protein kinase 1 L homeolog
  • 3-phosphoinositide dependent protein kinase-1
  • ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)
  • 3-phosphoinositide-dependent protein kinase 1
  • pyruvate dehydrogenase kinase, isozyme 1
  • pyruvate dehydrogenase kinase 1
  • Phosphoinositide-dependent kinase 1
  • 3'-phosphoinositide-dependent protein kinase 1
  • PDPK1
  • pdpk1.L
  • pdpk1
  • Pdpk1
  • ATP5G2
  • LOC100380750
  • pdk1
  • PDK1
  • Pdk1
  • pdk-1
Epitop
pSer241
59
32
29
27
27
26
17
15
15
15
13
13
8
7
7
6
6
5
5
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
475
248
241
22
13
12
11
9
6
5
4
3
2
1
1
1
1
1
1
Wirt
Maus
397
72
17
Klonalität
Monoklonal
Konjugat
Dieser PDPK1 Antikörper ist konjugiert mit PE
18
17
15
11
11
7
7
7
7
7
7
7
7
7
5
4
4
3
3
3
3
3
3
2
2
1
1
1
1
1
Applikation
Intracellular Staining (ICS)
332
182
134
91
70
66
45
35
26
11
10
6
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN1177136
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1177137 ICS Alexa Fluor 647 Mouse IgG1, kappa pSer241 Anmelden zum Anzeigen J66-653-44-17 1
1 ABIN1177138 ICS Alexa Fluor 488 Mouse IgG1, kappa pSer241 Anmelden zum Anzeigen J66-653-44-17 1

General

Antigen 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antikörper
Epitop pSer241
(59), (32), (29), (27), (27), (26), (17), (15), (15), (15), (13), (13), (8), (7), (7), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(475), (248), (241), (22), (13), (12), (11), (9), (6), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Wirt Maus
(397), (72), (17)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser PDPK1 Antikörper ist konjugiert mit PE
(18), (17), (15), (11), (11), (7), (7), (7), (7), (7), (7), (7), (7), (7), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Applikation Intracellular Staining (ICS)
(332), (182), (134), (91), (70), (66), (45), (35), (26), (11), (10), (6), (2), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PDPK1 Antikörper

Target Details PDPK1 Anwendungsinformationen Handhabung Referenzen für anti-PDPK1 Antikörper (ABIN1177136) Bilder
Marke BD Phosflow™
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Phosphorylated Human PDPK1 Peptide
Klon J66-653-44-17
Isotyp IgG1, kappa
Plasmids, Primers & others

Target Details PDPK1

Produktdetails anti-PDPK1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PDPK1 Antikörper (ABIN1177136) Bilder zurück nach oben
Antigen
Andere Bezeichnung PDPK1 (PDPK1 Antibody Abstract)
Hintergrund The serine/threonine kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDPK1, also known as PDK1) contributes to the activation of many important kinases in the insulin and IGF-1 signaling pathways. It acts downstream of phosphatidylinositol 3-kinase (PI3-kinase) to phosphorylate residues in the activation loops of many cellular kinases, including protein kinase B (PKB/Akt), PKC isoforms, p70 S6 kinase, and PDPK1 itself. The autophosphorylation of PDPK1 at serine 241 (S241) has recently been suggested to play a role in the regulation of PDPK1. It has been proposed that PDPK1 activity plays a key role in the regulation of various cellular events such as cell proliferation, differentiation, and apoptosis. The J666-653.44.17 monoclonal antibody recognizes the phosphorylated S241 in the activation loop of human PDPK1. The orthologous phosphorylation site in mouse and rat PDPK1 is S244.
Synonyms: PDK1 (pS241), PKB Kinase (pS241)
Pathways PI3K-Akt Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals

Anwendungsinformationen

Produktdetails anti-PDPK1 Antikörper Target Details PDPK1 Handhabung Referenzen für anti-PDPK1 Antikörper (ABIN1177136) Bilder zurück nach oben
Probenmenge 20 μL
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PDPK1 Antikörper Target Details PDPK1 Anwendungsinformationen Referenzen für anti-PDPK1 Antikörper (ABIN1177136) Bilder zurück nach oben
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Referenzen für anti-PDPK1 Antikörper (ABIN1177136)

Produktdetails anti-PDPK1 Antikörper Target Details PDPK1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Komander, Kular, Deak, Alessi, van Aalten: "Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding." in: The Journal of biological chemistry, Vol. 280, Issue 19, pp. 18797-802, 2005