Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
he combined action of CHIR99021 and forskolin markedly delayed neurological deficits and significantly reduced the tumor volume. We suggest that reprogramming technology may be a potential treatment strategy replacing the therapeutic paradigm of traditional treatment of malignant glioma, and a combination molecule comprising a GSK3 (zeige GSK3b ELISA Kits) inhibitor and a cAMP inducer could be the next generation of anticancer drugs.
Using integrated analysis of genome-wide short hairpin RNA (shRNA) screening data in combination with genome-wide gene expression data, the study identified GSK3 (zeige GSK3b ELISA Kits) as one of the key factors in p53 (zeige TP53 ELISA Kits)-mediated apoptosis in human lung cancer cells.
demonstrated that GSK-3alpha is regulated by CREB (zeige CREB1 ELISA Kits) in lung cancer and is required for the cell viability. These findings implicate CREB (zeige CREB1 ELISA Kits)-GSK-3alpha axis as a novel therapeutic target for lung cancer treatment
GSK3 acts through APC motifs R2 and B to regulate APC:Axin interactions, promoting high-throughput of betacatenin to destruction.
reveals that GSK-3alpha- and GSK-3beta (zeige GSK3b ELISA Kits)-regulated pathways can be responsible for stepwise transition to myelodysplastic syndromes and subsequent acute myeloid leukemia (zeige BCL11A ELISA Kits)
CHP3 (zeige TESC ELISA Kits) functions as a novel negative regulator of cardiomyocyte hypertrophy via inhibition of GSK3alpha/beta phosphorylation.
Elevated GSK3 protein kinase activity is associated with non-small cell lung carcinoma
GSK3A is redundant with GSK3B (zeige GSK3b ELISA Kits) in regulating drug-resistance and chemotherapy-induced necroptosis
ER stress-PERK-GSK3alpha/beta signaling promotes proatherogenic macrophage lipid accumulation
glycogen synthase kinase 3 alpha and beta activity is increased in foetal membranes after term and preterm labour
Data suggest that, in embryonic stem cells, Gsk3b (zeige GSK3b ELISA Kits)/Gsk3a phosphorylate splicing factors (Rbm8a (zeige RBM8A ELISA Kits), Srsf9 (zeige SFRS9 ELISA Kits), and Psf (zeige IL-3 ELISA Kits)) and nucleolar proteins (Npm1 (zeige GJA1 ELISA Kits) and Phf6 (zeige PHF6 ELISA Kits)); Gsk3b (zeige GSK3b ELISA Kits)/Gsk3a are key to alternative splicing of close to 190 genes. (Gsk3 (zeige GSK3b ELISA Kits) = glycogen synthase kinase-3; Rbm8a (zeige RBM8A ELISA Kits) = RNA binding motif protein 8a (zeige RBM8A ELISA Kits); Srsf9 (zeige SFRS9 ELISA Kits) = splicing factor (zeige SLU7 ELISA Kits), arginine-serine-rich 9; Psf (zeige IL-3 ELISA Kits) = replication protein Psf (zeige IL-3 ELISA Kits); Npm1 (zeige GJA1 ELISA Kits) = nucleophosmin 1 (zeige NPM1 ELISA Kits); Phf6 (zeige PHF6 ELISA Kits) = PHD finger protein 6 (zeige PHF6 ELISA Kits))
GSK3 (zeige GSK3b ELISA Kits) is regulated through mechanisms independent of N-terminal serine phosphorylation in order for beta-catenin (zeige CTNNB1 ELISA Kits) to be stabilized.
The expression of PI3K-insensitive GSK3 stimulates the production of adiponectin and protects from diet-induced metabolic syndrome.
Gsk3 (zeige GSK3b ELISA Kits) play a role in the maintenance of DNA methylation (zeige HELLS ELISA Kits) at a majority of the imprinted loci in embryonic stem cells
Sperm GSK3A is essential for male fertility.
The absence of oocyte GSK3 (zeige GSK3b ELISA Kits) isoforms in the periconceptional period does not alter fertility yet causes offspring cardiac hyperplasia, cardiovascular defects, and significant neonatal death.
results support the model that GSK3 (zeige GSK3b ELISA Kits) activity status is regulated by the circadian clock and that GSK3 (zeige GSK3b ELISA Kits) feeds back to regulate the molecular clock amplitude in the suprachiasmatic nucleus
Gsk3 (zeige GSK3b ELISA Kits)-deleted neurons expressing upper layer markers exhibited striking migration failure in all areas of the cortex.
PI3K/AKT (zeige AKT1 ELISA Kits)-mediated inhibitory phosphorylation of GSK3 (zeige GSK3b ELISA Kits) limits the regenerative outcome after peripheral nerve injury.
GSK3A serine phosphorylation was positively correlated with embryo development
signal pathways converged on inhibitory phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation
A mechanism whereby LRP6 (zeige LRP6 ELISA Kits) stabilizes beta-catenin (zeige CTNNB1 ELISA Kits) independently of Axin (zeige AXIN1 ELISA Kits) degradation by directly inhibiting GSK3 (zeige GSK3b ELISA Kits)'s phosphorylation of beta-catenin (zeige CTNNB1 ELISA Kits), is identified.
we demonstrate that PKA, PKC (zeige FYN ELISA Kits) and PI3K pathways crosstalk in porcine male germ cells to crucially regulate GSK3A phosphorylation which subsequently controls cell motility.
lycogen synthase kinase-3 (GSK3 (zeige GSK3b ELISA Kits)) was identified as a substrate of protein kinase c delta (zeige PKCd ELISA Kits) in breast cancer cells.
GSK3alpha, but not GSK3beta (zeige GSK3b ELISA Kits), is necessary in cardiomyocyte survival
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.
glycogen synthase kinase-3 alpha
, glycogen synthase kinase 3 alpha
, GSK-3 alpha
, serine/threonine-protein kinase GSK3A
, factor A