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Human Monoclonal BHLHE40 Primary Antibody für ELISA, WB - ABIN563685
Lecomte, Meugnier, Euthine, Durand, Freyssenet, Nemoz, Rome, Vidal, Lefai: A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation. in Molecular and cellular biology 2010
Show all 2 Pubmed References
Human Polyclonal BHLHE40 Primary Antibody für WB - ABIN654604
Wang, Reiser-Erkan, Michalski, Raggi, Quan, Yupei, Friess, Erkan, Kleeff: Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. in Biochemical and biophysical research communications 2010
Show all 2 Pubmed References
DEC1 is involved in hypoxia-induced EMT (zeige ITK Antikörper) processes via negatively regulating E-cadherin (zeige CDH1 Antikörper) expression in HepG2 cells.
This study was performed to test the hypothesis that the SHP (zeige LAMC1 Antikörper) gene is a target gene of DEC1. Cotransfection demonstrated that DEC1 repressed the SHP (zeige LAMC1 Antikörper) promoter and attenuated the transactivation of the classic circadian activator complex of Clock/Bmal1 (zeige ARNTL Antikörper).
Dec1 is a prognostic factor for the clinical outcome and a predictive factor for the response to TMZ chemotherapy in patients with glioma
decreases of CES and CYP3A4 (zeige CYP3A4 Antikörper) expression and enzymatic activities induced by Fluoxetine are through decreasing PXR (zeige NR1I2 Antikörper) and increasing DEC1 in HepG2 cells
Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 (zeige ASS1 Antikörper) is regulated by DEC1, HIF-1alpha (zeige HIF1A Antikörper), and c-Myc (zeige MYC Antikörper) transcription network and is independent of ASS1 (zeige ASS1 Antikörper) promoter DNA methylation (zeige HELLS Antikörper).
High BHLHE40 expression is associated with glioblastomas.
STRA13 may be essential for the progression of atopic dermatitis by interacting with hsa (zeige CD24 Antikörper)-miR (zeige MLXIP Antikörper)-148b and hsamiR- 152.
BHLHE40 was identified as a viable candidate for which a droplet digital PCR assay for demethylation was developed. The assay revealed high demethylation in activated NK cells and low demethylation in naive NK, T- and B-cells. We conclude the NK cell methylome is plastic with potential for remodeling.
findings suggested that posttranslational modification of DEC1 in the form of SUMOylation may serve as a key factor that regulates the function of DEC1 in vivo
Study conclude that DeltaNp63 is a novel target of DEC1 and HDAC2 (zeige HDAC2 Antikörper) and modulates the efficacy of HDAC (zeige HDAC3 Antikörper) inhibitors in growth suppression and keratinocyte differentiation.
Expression of DEC1 is evolutionally conserved in zebrafish.
This study aimed to lay the groundwork to further study of Bhlhe40 function at myogenesis and adipogenesis in bovine and should significantly contribute to cattle breeding and genetics through MAS (zeige MAS1 Antikörper) program
Loss of Bhlhe40 expression is associated with impaired long term potentiation and long term depression at CA1 (zeige CA1 Antikörper) synapses.
This study demonstrates that downregulation of DEC1 contributes to MPP(+) -induced neurotoxicity by suppressing PI3K/Akt/GSK3beta pathway.
These results indicate that Bhlhe40 works as a cofactor of T-bet for enhancing IFN-gamma (zeige IFNG Antikörper) production in iNKT cells.
Bhlhe40 expression identifies encephalitogenic Th cells and defines a PTX-IL-1 (zeige IL1A Antikörper)-Bhlhe40 pathway active in experimental autoimmune encephalomyelitis.
Collectively, the data obtained in this study suggest that DEC1 is a novel negative regulator of hepatic FGF21 (zeige FGF21 Antikörper) expression
establishes a crucial role of Bhlhe40 in mediating the repressive effect of hypoxia on myogenic differentiation and suggests that inhibition of Bhlhe40 or p53 (zeige TP53 Antikörper) may facilitate muscle regeneration after ischemic injuries
There was an inverse relationship between DEC1 expression and AMPK (zeige PRKAA1 Antikörper) activity. Our results suggest that DEC1 negatively regulates AMPK (zeige PRKAA1 Antikörper) activity via LKB1 (zeige STK11 Antikörper)
Data show that the bHLH transcription factors SHARP1 and SHARP2 are involved in cognitive processing by controlling insulin-like growth factor II (Igf2) expression and associated signaling cascades.
Data indicate that bHLH transcription factors Bhlhe40 interacts with PGC-1alpha protein (PGC-1alpha) and represses its transcriptional activity.
abnormal sleep and certain (endo)phenotypes of psychiatric diseases may be caused by common mechanisms involving components of the molecular clock including SHARP1 (zeige BHLHE41 Antikörper) and SHARP2.
This gene encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differentiation.
basic helix-loop-helix domain containing, class B, 2
, class B basic helix-loop-helix protein 2
, class E basic helix-loop-helix protein 40
, differentially expressed in chondrocytes 1
, differentially expressed in chondrocytes protein 1
, differentiated embryo chondrocyte expressed gene 1
, enhancer-of-split and hairy-related protein 2
, stimulated by retinoic acid gene 13 protein
, bHLH protein DEC1
, Class B basic helix-loop-helix protein 2
, basic helix-loop-helix domain containing class B2 protein
, basic helix-loop-helix family, member e40
, class E basic helix-loop-helix protein 40-like
, E47 interaction protein 1
, basic helix-loop-helix domain containing, class B2
, cytokine response gene 8
, eip1 (E47 interaction protein 1)
, enhancer-of split and hairy-related protein 2
, stimulated by retinoic acid 14