Ku, Liang, Jung, Oh: "Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX." in: Cell research, Vol. 21, Issue 4, pp. 627-41, (2011) (PubMed).
Target
Bak BH3
Hintergrund
This peptide, generated from the BH3 domain of Bak (Flu-BakBH3), has been shown to have high-affinity binding to a surface pocket of the Bcl-XL protein that is required for its death antagonist function. Synonym: Bak BH3