This is a synthetic peptide designed for use in combination with anti-XPA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
XPA
Reaktivität: Human, Hund, Maus
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
XPA
(Xeroderma Pigmentosum, Complementation Group A (XPA))
Synonyme
CG6358 Peptide, DhR14 Peptide, DhXPA Peptide, DmXPA Peptide, Dmel\\CG6358 Peptide, Dxpa Peptide, EG:EG0007.8 Peptide, XPAC Peptide, XPA_DROME Peptide, Xpa Peptide, dmXPA Peptide, dxpa Peptide, XP1 Peptide, AI573865 Peptide, Xpac Peptide, xpac Peptide, xxpa Peptide, Xeroderma pigmentosum group A-like Peptide, XPA, DNA damage recognition and repair factor Peptide, xeroderma pigmentosum, complementation group A Peptide, xeroderma pigmentosum, complementation group A L homeolog Peptide, Xpac Peptide, XPA Peptide, Xpa Peptide, xpa.L Peptide
Hintergrund
This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: XP1, XPAC
Protein Interaction Partner: ATM,ATR,DDB2,ERCC1,ERCC6,GPN1,GTF2E2,GTF2H1,PRKDC,RASSF1,RPA1,RPA2,RPA4,XAB2,EP300,ERCC1,ERCC6,GPN1,GTF2E2,MSH2,MSH3,RPA1,RPA2,RPA4,XAB2