WNT10B
(Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))
Protein Region
Middle Region
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-WNT10B antibody (Catalog #: ARP41239_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
WNT10B
(Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))
Synonyme
WNT10B Peptide, Xwnt-10b Peptide, Xwnt10b Peptide, wnt-12 Peptide, Wnt12 Peptide, SHFM6 Peptide, WNT-12 Peptide, Xwnt-10 Peptide, wnt10 Peptide, wnt10-A Peptide, Zwnt[d] Peptide, wnt10br Peptide, wnt[d] Peptide, Wnt family member 10B Peptide, wingless-type MMTV integration site family, member 10B Peptide, Wnt family member 10B S homeolog Peptide, wingless-type MMTV integration site family, member 10b Peptide, WNT10B Peptide, wnt10b Peptide, Wnt10b Peptide, wnt10b.S Peptide
Hintergrund
WNT10B is the ligand for members of the frizzled family of seven transmembrane receptors. WNT10B is a probable developmental protein. It may be a signaling molecule which affects the development of discrete regions of tissues. WNT10B is likely to signal over only few cell diameters.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96 % identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.