This is a synthetic peptide designed for use in combination with anti-SUFU antibody (Catalog #: ARP33018_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
SUFU is a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes. SUFU encodes a component of the sonic hedgehog (SHH, MIM 600725)/patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PRO1280, SUFUH, SUFUXL
Protein Interaction Partner: BTRC,GLI1,GLI2,GLI3,GLIS3,HMGA1,HNRNPA1,LGALS3,MAPKSP1,MID1IP1,NCOA3,PEX26,PIAS1,QPRT,RBPJ,RCN3,RNF19A,SAP18,SETDB1,STK36,SUFU,ZNF219,ZNF263,ZNF446,ZNF764,GLI1,GLI2,GLI3,GLIS3,MID1IP1,PEX26,QPRT,RCN3,SUFU,ZNF263,ZNF446,ZNF764