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SMAD, Mothers Against DPP Homolog 7 (SMAD7) Peptid

SMAD7 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN984106
  • Target Alle SMAD7 Produkte
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SMAD7 antibody (Catalog #: ARP32008_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Synonyme
    CRCS3 Peptide, MADH7 Peptide, MADH8 Peptide, Smad7a Peptide, Madh7 Peptide, Smad10 Peptide, madh7 Peptide, xsmad7 Peptide, wu:fj60c10 Peptide, SMAD family member 7 Peptide, SMAD family member 7 L homeolog Peptide, SMAD7 Peptide, Smad7 Peptide, smad7.L Peptide, smad7 Peptide
    Hintergrund
    Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.

    Alias Symbols: CRCS3, MADH7, MADH8

    Protein Interaction Partner: SMURF1,SMURF2,ACVR1B,AKT1,ASH1L,AXIN1,BMPR1B,CTNNB1,CXXC5,DVL1,EP300,ERBB2IP,HAT1,HEYL,KDM2A,MAP2K3,MAP2K6,MAP3K7,MAPK14,MBD1,MYOD1,PARD3,PIAS1,PIAS4,RNF111,SASH3,SMAD6,SMAD7,SMURF1,SMURF2,SOX13,SOX5,SOX7,STAMBP,STAMBPL1,STRAP,TAB1,TGFBR1,TGFBR2,TTF1,TTF2,XRCC6,YAP1,ZBTB11,ZBTB44,ZNF107,ACVR1B,AKT1,BMPR1A,CTNNB1,DVL1,EP300,ERBB2IP,LEF1,MAP2K3,MAP2K6,MAP3K7,MAPK14,PARD3B,PIAS4,RNF111,SMAD2,SMAD3,SMAD4,SMAD6,SMURF1,SMURF2,STAMBP,STRAP,TAB1,TGFBR1,TGFBR2,Wwp2,YAP1

    Protein Size: 426
    Molekulargewicht
    46 kDa
    Gen-ID
    4092
    NCBI Accession
    NM_005904, NP_005895
    UniProt
    O15105
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