Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (N-Term) Peptid

SLC12A1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983813
  • Target Alle SLC12A1 Produkte
    SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    NEKKSRGFFN YQASIFAENF GPRFTKGEGF FSVFAIFFPA ATGILAGANI
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-SLC12A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1))
    Synonyme
    slc12a1 Peptide, SLC12A1 Peptide, DKFZp469A2020 Peptide, BSC1 Peptide, NKCC2 Peptide, Nkcc2 Peptide, AI788571 Peptide, D630042G03Rik Peptide, mBSC1 Peptide, urehr3 Peptide, si:ch211-220f12.1 Peptide, solute carrier family 12 member 1 Peptide, solute carrier family 12, member 1 Peptide, si:ch211-220f12.1 Peptide, SLC12A1 Peptide, Slc12a1 Peptide
    Hintergrund
    This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

    Alias Symbols: BSC1, NKCC2

    Protein Size: 430
    Molekulargewicht
    47 kDa
    Gen-ID
    6557
    NCBI Accession
    NM_000338, NP_000329
    UniProt
    Q8IUN5
Sie sind hier:
Kundenservice