This is a synthetic peptide designed for use in combination with anti-RFC1 Antibody(ARP56522_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.
Alias Symbols: A1, MGC51786, MHCBFB, PO-GA, RECC1, RFC, RFC140
Protein Interaction Partner: BRCA1,BRD4,CASP3,CCND1,CDK4,CEBPA,HDAC1,MYOC,PCNA,RELA,RFC1,RFC2,RFC3,SMC1A,TCEAL1,ATM,BLM,BRCA1,BRD4,CCND1,CDK4,CHTF18,HDAC1,KIT,MLH1,MRE11A,MSH2,MSH6,NBN,PCNA,PMS1,RAD17,RAD50,RB1,RELA,RFC2,RFC3,RFC4,RFC5,SMARCA4,SSBP3,TP53,XRCC5,ZSCAN1