Plasminogen Activator, Tissue (PLAT) (Middle Region) Peptid

Details zu Produkt Nr. ABIN981837, Anbieter: Anmelden zum Anzeigen
Proteinname
  • T-PA
  • TPA
  • AU020998
  • AW212668
  • D8Ertd2e
  • tPA
  • PATISS
  • tpa
  • Plat
  • plat
  • t-pa
  • plasminogen activator, tissue type
  • plasminogen activator, tissue
  • chromosome 20 open reading frame 181
  • plasminogen activator, tissue L homeolog
  • PLAT
  • Plat
  • plat
  • C20orf181
  • plat.L
Protein Region
Middle Region
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-PLAT Antikörper (Plasminogen Activator, Tissue) (Middle Region) (ABIN2787342)
Sequenz TVILGRTYRV VPGEEEQKFE VEKYIVHKEF DDDTYDNDIA LLQLKSDSSR
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PLAT Antibody(ARP57691_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Proteinname Plasminogen Activator, Tissue (PLAT)
Hintergrund This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Alias Symbols: DKFZp686I03148, T-PA, TPA

Protein Interaction Partner: ANXA2,CALR,CKAP4,CLEC3B,F10,FGA,GRIN1,HMGB1,KRT8,LAMA1,LAMA3,LRP1,LRP1B,MAPK1,MAPK3,PLAT,PLAU,PLG,SERPINA5,SERPINE1,SERPING1,SERPINI1,SPARC,ANXA2,CALR,CLEC3B,F10,F2,FGA,FN1,HMGB1,KRT8,LAMA1,LAMA5,LRP1,PLAU,SERPINA5,SERPINE1,SERPINI1

Protein Size: 516
Molekulargewicht 53 kDa
Gen-ID 5327
NCBI Accession NM_033011, NP_127509
Applikations-hinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.