Plasminogen Activator, Tissue (PLAT) (Middle Region) Peptid
PLAT
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle PLAT Produkte
- PLAT (Plasminogen Activator, Tissue (PLAT))
- Protein Region
- Middle Region
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- TVILGRTYRV VPGEEEQKFE VEKYIVHKEF DDDTYDNDIA LLQLKSDSSR
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PLAT Antibody(ARP57691_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- PLAT (Plasminogen Activator, Tissue (PLAT))
- Synonyme
- T-PA Peptide, TPA Peptide, AU020998 Peptide, AW212668 Peptide, D8Ertd2e Peptide, tPA Peptide, PATISS Peptide, tpa Peptide, Plat Peptide, plat Peptide, t-pa Peptide, plasminogen activator, tissue type Peptide, plasminogen activator, tissue Peptide, chromosome 20 open reading frame 181 Peptide, plasminogen activator, tissue L homeolog Peptide, PLAT Peptide, Plat Peptide, plat Peptide, C20orf181 Peptide, plat.L Peptide
- Hintergrund
-
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: DKFZp686I03148, T-PA, TPA
Protein Interaction Partner: ANXA2,CALR,CKAP4,CLEC3B,F10,FGA,GRIN1,HMGB1,KRT8,LAMA1,LAMA3,LRP1,LRP1B,MAPK1,MAPK3,PLAT,PLAU,PLG,SERPINA5,SERPINE1,SERPING1,SERPINI1,SPARC,ANXA2,CALR,CLEC3B,F10,F2,FGA,FN1,HMGB1,KRT8,LAMA1,LAMA5,LRP1,PLAU,SERPINA5,SERPINE1,SERPINI1
Protein Size: 516 - Molekulargewicht
- 53 kDa
- Gen-ID
- 5327
- NCBI Accession
- NM_033011, NP_127509
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