Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (N-Term) Peptid

Details zu Produkt Nr. ABIN981770, Anbieter: Anmelden zum Anzeigen
Proteinname
  • DOD
  • UBL5
  • dod
  • ubl5
  • pin1
  • pin1a
  • 0610025L01Rik
  • D9Bwg1161e
  • pin1b
  • zgc:73206
  • PPIase pin1
  • MdPin1
  • Pin1
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog
  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
  • peptidyl-prolyl cis-trans isomerase Pin1
  • PIN1
  • Pin1
  • pin1
  • pin1.S
  • pin1.L
  • ppiD
  • PITG_11123
  • LOC103419188
Protein Region
N-Term
Spezies
Human
9
8
7
4
4
4
4
1
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) (N-Term) Antikörper (ABIN2789425)
Sequenz RPSGNSSSGG KNGQGEPARV RCSHLLVKHS QSRRPSSWRQ EKITRTKEEA
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PIN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Proteinname
Hintergrund Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

Alias Symbols: DOD, UBL5

Protein Interaction Partner: CCND1,CDC27,PKMYT1,PLK1,RAF1,TP73,TP73,APP,BCL2,CCNB1,CCNE1,CDC25C,CDC27,CDK1,CDK9,CHPF,CSNK2A1,CSNK2A2,CSNK2B,CTNNB1,DAB2,DDX24,FASLG,GGA2,GPAA1,GPHN,JUN,KIF20B,KLHL20,LEPR,MAPT,MDFI,MTFR1,NCOA3,NEK6,NFATC2,NONO,PKMYT1,PLK1,POLR2A,PTOV1,PTPN1,RAB4A,RAF1,

Protein Size: 163
Molekulargewicht 18 kDa
Gen-ID 5300
NCBI Accession NM_006221, NP_006212
UniProt Q13526
Applikations-hinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.