Pim-1 Oncogene (PIM1) (N-Term) Peptid

Details zu Produkt Nr. ABIN981768, Anbieter: Anmelden zum Anzeigen
Proteinname
  • PIM
  • Pim-1
  • cb1068
  • fj47b05
  • pim2
  • wu:fj47b05
  • PIM1
  • pim
  • pim-1
  • pim3
  • Pim-1 proto-oncogene, serine/threonine kinase
  • proviral integration site 1
  • Pim-2 proto-oncogene, serine/threonine kinase
  • Pim-1 proto-oncogene, serine/threonine kinase L homeolog
  • PIM1
  • Pim1
  • pim2
  • pim1
  • pim1.L
Protein Region
N-Term
Spezies
Human
2
1
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-PIM1 Antikörper (Pim-1 Oncogene) (N-Term) (ABIN2786676)
Sequenz MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PIM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).

Alias Symbols: PIM

Protein Size: 313
Molekulargewicht 36 kDa
Gen-ID 5292
NCBI Accession NM_001243186, NP_001230115
Applikations-hinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.