Protein Inhibitor of Activated STAT, 3 (PIAS3) (Middle Region) Peptid

Details zu Produkt Nr. ABIN981734, Anbieter: Anmelden zum Anzeigen
Proteinname
  • PIAS3
  • Pias3l
  • ZMIZ5
  • protein inhibitor of activated STAT 3
  • protein inhibitor of activated STAT, 3
  • protein inhibitor of activated STAT 3 L homeolog
  • PIAS3
  • pias3
  • Pias3
  • pias3.L
Protein Region
Middle Region
Spezies
Human
5
2
2
2
2
2
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Geblockter Antikörper anti-PIAS3 Antikörper (Protein Inhibitor of Activated STAT, 3) (Middle Region) (ABIN2777575)
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PIAS3 antibody (Catalog #: ARP32763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: FLJ14651, ZMIZ5

Protein Interaction Partner: GEMIN4,ZFHX3,AR,ATF7IP,EP300,ESR1,ESR2,GEMIN4,GFI1,HABP4,HDAC1,HMGA2,MITF,NCOA2,NR3C2,OPN1LW,PGR,PRPF40A,RELA,SERBP1,SKIL,SMAD2,SMAD3,SMAD4,STAT3,TBP,ZFHX3,AR,CREBBP,EP300,GFI1,HMGA2,MITF,RELA,SIAH1,SIAH2,SMAD2,SMAD3,SMAD4,STAT3,TRIM32,UBC,ZMIZ1,ZMIZ2

Protein Size: 628
Molekulargewicht 68 kDa
Gen-ID 10401
NCBI Accession NM_006099, NP_006090
UniProt Q9Y6X2
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.