Polyhomeotic Homolog 2 (PHC2) (N-Term) Peptid

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Proteinname
  • polyhomeotic homolog 2 L homeolog
  • phc2.L
Protein Region
N-Term
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-Polyhomeotic Homolog 2 (Drosophila) (PhC2) (N-Term) Antikörper (ABIN2784482)
Sequenz GGSGRPTGPQ ISVYSGIPDR QTVQVIQQAL HRQPSTAAQY LQQMYAAQQQ
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PHC2 Antibody(ARP51251_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: EDR2, HPH2, MGC163502, PH2

Protein Interaction Partner: MAPKAPK3,AFG3L2,BMI1,BSDC1,FHL3,GFI1B,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1,TMEM70,AFG3L2,BMI1,BSDC1,Bmi1,Cbx2,FHL3,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1

Protein Size: 858
Molekulargewicht 91 kDa
Gen-ID 1912
NCBI Accession NM_198040, NP_932157
UniProt Q8IXK0
Applikations-hinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.