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TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Peptid

TAB2 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN979779
  • Target Alle TAB2 Produkte
    TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-MAP3K7IP2 antibody (Catalog #: ARP32402_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
    Synonyme
    CHTD2 Peptide, MAP3K7IP2 Peptide, 1110030N06Rik Peptide, A530078N03Rik Peptide, Map3k7ip2 Peptide, mKIAA0733 Peptide, map3k7ip2 Peptide, zgc:77446 Peptide, TGF-beta activated kinase 1/MAP3K7 binding protein 2 Peptide, TAB2 Peptide, Tab2 Peptide, tab2 Peptide
    Hintergrund
    MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

    Alias Symbols: CHTD2, MAP3K7IP2

    Protein Interaction Partner: EIF2AK2,HDAC3,IRAK1,MAP3K7,NR2C2,TAB1,TNFRSF11A,TRAF2,TRAF6,XIAP,CD82,CNTN2,CS,HDAC1,HDAC3,HDAC5,IRAK1,MAP3K7,Map3k7,NCOR1,NFKB1,NUMBL,RIPK1,TAB1,TAB2,TAB3,TBL1X,TNFRSF11A,TRAF2,TRAF6,XIAP

    Protein Size: 693
    Molekulargewicht
    76 kDa
    Gen-ID
    23118
    NCBI Accession
    NM_015093, NP_055908
    UniProt
    Q9NYJ8
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