TAB2
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-MAP3K7IP2 antibody (Catalog #: ARP32402_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Alias Symbols: CHTD2, MAP3K7IP2
Protein Interaction Partner: EIF2AK2,HDAC3,IRAK1,MAP3K7,NR2C2,TAB1,TNFRSF11A,TRAF2,TRAF6,XIAP,CD82,CNTN2,CS,HDAC1,HDAC3,HDAC5,IRAK1,MAP3K7,Map3k7,NCOR1,NFKB1,NUMBL,RIPK1,TAB1,TAB2,TAB3,TBL1X,TNFRSF11A,TRAF2,TRAF6,XIAP