Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-KHDRBS1 antibody (Catalog #: ARP40665_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
Alias Symbols: FLJ34027, Sam68, p62, p68
Protein Interaction Partner: GRAP2,GRB2,HCK,HNRNPK,HNRNPK,LCK,PIK3R1,RASA1,SRC,src,BTK,CBL,CDK1,CREBBP,DHX9,EMG1,FNBP4,FYN,GRAP,GRAP2,GRB2,HCK,HNRNPK,INSR,ITK,JAK3,KHDRBS1,KHDRBS3,LCK,LYN,MAPK1,NCF1,NCK1,PIK3R1,PLCG1,PLCG2,PRMT1,PTK6,PTPN6,RAPSN,RASA1,SMAD2,SMARCA2,SRC,STAT3,STUB1,TUBB3,UBA52,WBP4,YTHDC1,BTK,CREBBP,CRK,DHX9,EMG1,FNBP4,FYN,GRAP2,GRB2,Grap2,HNRNPK,INSR,IRS1,ITK,KHDRBS1,KHDRBS2,Khdrbs3,LCK,NCF1,NCK1,PACSIN1,PACSIN2,PACSIN3,PIK3R1,PLCG1,PRMT1,PTK6,RAPSN,RASA1,SRC,STAT3,STUB1,TNFSF11,TUBB3,WBP4,YTHDC1