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High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (Middle Region) Peptid

HMGN1 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN978068
  • Target Alle HMGN1 Produkte
    HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-HMGN1 antibody (Catalog #: ARP32627_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
    Synonyme
    HMG14 Peptide, hmg14 Peptide, hmgn1 Peptide, hmgn1b Peptide, HMG-14 Peptide, Hmg14 Peptide, high mobility group nucleosome binding domain 1 Peptide, high mobility group nucleosome binding domain 1 S homeolog Peptide, high mobility group nucleosomal binding domain 1 Peptide, non-histone chromosomal protein HMG-14 Peptide, HMGN1 Peptide, hmgn1.S Peptide, hmgn1 Peptide, Hmgn1 Peptide, LOC785479 Peptide
    Hintergrund
    Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425

    Protein Interaction Partner: EP300,HMGN1,HMGN2,IRF2,PRKACA,PRKCA,RPS6KA3,RPS6KA4,RPS6KA5,YWHAZ,HMGN1,YWHAZ

    Protein Size: 100
    Molekulargewicht
    11 kDa
    Gen-ID
    3150
    NCBI Accession
    NM_004965, NP_004956
    UniProt
    P05114
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