HMGN1
(High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
Protein Region
Middle Region
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-HMGN1 antibody (Catalog #: ARP32627_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
HMGN1
Reaktivität: Human, Rind (Kuh), Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
HMGN1
(High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
Synonyme
HMG14 Peptide, hmg14 Peptide, hmgn1 Peptide, hmgn1b Peptide, HMG-14 Peptide, Hmg14 Peptide, high mobility group nucleosome binding domain 1 Peptide, high mobility group nucleosome binding domain 1 S homeolog Peptide, high mobility group nucleosomal binding domain 1 Peptide, non-histone chromosomal protein HMG-14 Peptide, HMGN1 Peptide, hmgn1.S Peptide, hmgn1 Peptide, Hmgn1 Peptide, LOC785479 Peptide
Hintergrund
Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425
Protein Interaction Partner: EP300,HMGN1,HMGN2,IRF2,PRKACA,PRKCA,RPS6KA3,RPS6KA4,RPS6KA5,YWHAZ,HMGN1,YWHAZ