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General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1) Peptid

GTF2E1 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN977755
  • Target Alle GTF2E1 Produkte
    GTF2E1 (General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1))
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-GTF2E1 antibody (Catalog #: P100892_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GTF2E1 (General Transcription Factor IIE, Polypeptide 1, alpha 56kDa (GTF2E1))
    Synonyme
    2610024P03Rik Peptide, 56kDa Peptide, AI303800 Peptide, FE Peptide, TFIIE-A Peptide, DDBDRAFT_0168201 Peptide, DDBDRAFT_0168202 Peptide, DDBDRAFT_0231096 Peptide, DDB_0168201 Peptide, DDB_0168202 Peptide, DDB_0231096 Peptide, DDBDRAFT_0217176 Peptide, DDBDRAFT_0217177 Peptide, DDBDRAFT_0266401 Peptide, DDB_0217176 Peptide, DDB_0217177 Peptide, DDB_0266401 Peptide, TF2E1 Peptide, si:ch211-194d6.2 Peptide, gtf2e1 Peptide, tfiiealpha Peptide, general transcription factor II E, polypeptide 1 (alpha subunit) Peptide, general transcription factor IIE subunit 1 Peptide, transcription factor IIE Peptide, general transcription factor IIE subunit 2 Peptide, general transcription factor IIE, polypeptide 2, beta 34kDa Peptide, general transcription factor IIE, polypeptide 1, alpha Peptide, general transcription factor IIE subunit 1 L homeolog Peptide, Gtf2e1 Peptide, gtf2e1-1 Peptide, gtf2e1-2 Peptide, GTF2E2 Peptide, GTF2E1 Peptide, gtf2e1 Peptide, gtf2e1.L Peptide
    Hintergrund
    The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57,000 (TFIIE-alpha) and 34,000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation

    Alias Symbols: FE, TF2E1, TFIIE-A

    Protein Interaction Partner: AES,ERCC3,GTF2A1,GTF2A2,GTF2B,GTF2E2,GTF2F2,GTF2H1,GTF2H4,SND1,TAF6,TBP,TCEA1,TRIM24,AES,BRCA1,ERCC3,GTF2A1,GTF2B,GTF2E2,GTF2F1,GTF2F2,GTF2H4,MDM2,MED21,POLR2A,SND1,TAF1,TAF11,TAF6,TBP,TCEA1,TRIM24

    Protein Size: 439
    Molekulargewicht
    49 kDa
    Gen-ID
    2960
    NCBI Accession
    NM_005513, NP_005504
    UniProt
    P29083
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