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Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) Peptid
GCLC
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
Produktdetails
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Target
Alle GCLC Produkte
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Protein Region
Middle Region
Spezies
Human
Quelle
Alle Wirte für GCLC Peptide
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Sequenz
RISKSRYDSI DSYLSKCGEK YNDIDLTIDK EIYEQLLQEG IDHLLAQHVA
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-GCLC Antibody(ARP54577_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Aufreinigung
Purified
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigendetails
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Target
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Synonyme
GCLC Peptide, gclc Peptide, MGC146287 Peptide, 2259 Peptide, CG2259 Peptide, DmGCLC Peptide, DmGCS Peptide, DmGCSh Peptide, Dmel\\CG2259 Peptide, GCL Peptide, GCLc Peptide, GCSh Peptide, Gcs Peptide, Gcsh Peptide, DDBDRAFT_0186120 Peptide, DDBDRAFT_0231403 Peptide, DDB_0186120 Peptide, DDB_0231403 Peptide, GCS Peptide, GLCL Peptide, GLCLC Peptide, D9Wsu168e Peptide, GLCL-H Peptide, Ggcs-hs Peptide, Glclc Peptide, cb1049 Peptide, fe36e11 Peptide, wu:fe36e11 Peptide, glutamate-cysteine ligase catalytic subunit Peptide, glutamate-cysteine ligase, catalytic subunit Peptide, Glutamate-cysteine ligase catalytic subunit Peptide, gamma glutamylcysteine synthetase Peptide, glutamate-cysteine ligase, catalytic subunit L homeolog Peptide, glutamate-cysteine ligase, catalytic subunit S homeolog Peptide, gamma-glutamylcysteine synthetase Peptide, GCLC Peptide, gclc Peptide, Gclc Peptide, LbGCS Peptide, gcsA Peptide, gclc.L Peptide, gclc.S Peptide, GSH1 Peptide
Hintergrund
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC is the catalytic subunit of 637 amino acids with a calculated molecular weight of 72.773 kDa. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia. Alias Symbols: GCL, GCS, GLCL, GLCLC Protein Size: 637
Molekulargewicht
73 kDa
Gen-ID
2729
NCBI Accession
NM_001498 , NP_001489
UniProt
P48506
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Peptide
GCLC
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) Peptid (ABIN977333)