Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) Peptid

Details zu Produkt Nr. ABIN977333, Anbieter: Anmelden zum Anzeigen
Proteinname
  • GCLC
  • gclc
  • MGC146287
  • 2259
  • CG2259
  • DmGCLC
  • DmGCS
  • DmGCSh
  • Dmel\\CG2259
  • GCL
  • GCLc
  • GCSh
  • Gcs
  • Gcsh
  • DDBDRAFT_0186120
  • DDBDRAFT_0231403
  • DDB_0186120
  • DDB_0231403
  • GCS
  • GLCL
  • GLCLC
  • D9Wsu168e
  • GLCL-H
  • Ggcs-hs
  • Glclc
  • cb1049
  • fe36e11
  • wu:fe36e11
  • glutamate-cysteine ligase catalytic subunit
  • glutamate-cysteine ligase, catalytic subunit
  • Glutamate-cysteine ligase catalytic subunit
  • gamma glutamylcysteine synthetase
  • glutamate-cysteine ligase, catalytic subunit L homeolog
  • glutamate-cysteine ligase, catalytic subunit S homeolog
  • gamma-glutamylcysteine synthetase
  • GCLC
  • gclc
  • Gclc
  • LbGCS
  • gcsA
  • gclc.L
  • gclc.S
  • GSH1
Protein Region
Middle Region
Spezies
Human
3
2
2
2
2
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) Antikörper (ABIN2785780)
Sequenz RISKSRYDSI DSYLSKCGEK YNDIDLTIDK EIYEQLLQEG IDHLLAQHVA
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-GCLC Antibody(ARP54577_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC is the catalytic subunit of 637 amino acids with a calculated molecular weight of 72.773 kDa. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.

Alias Symbols: GCL, GCS, GLCL, GLCLC

Protein Size: 637
Molekulargewicht 73 kDa
Gen-ID 2729
NCBI Accession NM_001498, NP_001489
UniProt P48506
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.