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DNA Cross-Link Repair 1C (DCLRE1C) (C-Term) Peptid

DCLRE1C Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN975625
  • Target Alle DCLRE1C Produkte
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-DCLRE1C antibody (Catalog #: ARP51165_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    Synonyme
    artemis Peptide, A-SCID Peptide, DCLREC1C Peptide, RS-SCID Peptide, SCIDA Peptide, SNM1C Peptide, hSNM1C Peptide, Snm1l Peptide, nuclease Peptide, 9930121L06Rik Peptide, AI661365 Peptide, Art Peptide, DNA cross-link repair 1C Peptide, DCLRE1C Peptide, Dclre1c Peptide
    Hintergrund
    DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).

    Alias Symbols: A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C, hSNM1C

    Protein Interaction Partner: TP53BP1,ATM,BRCA1,MRE11A,NBN,PRKDC,RAD50,TP53BP1,PRKDC

    Protein Size: 572
    Molekulargewicht
    65 kDa
    Gen-ID
    64421
    NCBI Accession
    NM_001033857, NP_001029029
    UniProt
    Q96SD1
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