This is a synthetic peptide designed for use in combination with anti-CDH1 Antibody(ARP59265_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Alias Symbols: Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Protein Interaction Partner: ZEB1,CAV1,CTNNB1,CTNNB1,CTNNB1,CTNND1,EGFR,ACTR3,ANAPC7,ARHGAP32,ARVCF,CA9,CASP3,CASP8,CBLL1,CDH1,CSE1L,CSNK2A1,CTNNA1,CTNNB1,CTNND1,CTNND2,EGFR,ERBB2IP,EZR,GNA12,GNA13,GSK3B,HDAC1,HDAC2,IQGAP1,IRS1,ITGAE,ITGB7,JUP,NDRG1,NEDD9,PKD1,PPP1CA,PSEN1,PTPN14,PTP