Calcium Modulating Ligand (CAMLG) (N-Term) Peptid
CAMLG
Reaktivität: Human
Wirt: Synthetic
BP, WB
-
- Target Alle CAMLG Produkte
- CAMLG (Calcium Modulating Ligand (CAMLG))
- Protein Region
- N-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CAMLG antibody (Catalog #: ARP48191_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CAMLG (Calcium Modulating Ligand (CAMLG))
- Synonyme
- MGC53900 Peptide, CAML Peptide, AI385748 Peptide, Camlg Peptide, Caml Peptide, calcium modulating ligand L homeolog Peptide, calcium modulating ligand Peptide, camlg.L Peptide, CAMLG Peptide, camlg Peptide, Caml Peptide, Camlg Peptide
- Hintergrund
-
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Alias Symbols: CAML, MGC163197
Protein Interaction Partner: IER3,EGFR,PKHD1,TNFRSF13B,EGFR,PPIB,TNFRSF13B
Protein Size: 296 - Molekulargewicht
- 33 kDa
- Gen-ID
- 819
- NCBI Accession
- NM_001745, NP_001736
- UniProt
- P49069
-
Sie sind hier:
