N-Formyl-Met-Leu-Phe Peptid

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Reinigung The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Reinheit > 95 %
Hintergrund N-formyl-methionyl-leucyl-phenylalanine (fMLP), the chemotactic bacterial peptide, was able to specifically attenuate Ca2+ mobilization in human phagocytes induced by SAA, but only at very high concentrations. The bacterial peptide N-formyl-methionyl-leucyl-phenylalanine (fMLF) is one of the first identified and highly potent leukocyte chemoattractants. fMLF interacts with at least two human cell receptors formyl peptide receptor (FPR) and its variant formyl peptide receptor-like 1 (FPRL1), both are members of the seven transmembrane domain, G protein-coupled receptor (GPCR) family.
CAS-Nummer 59880-97-6
Beschränkungen Nur für Forschungszwecke einsetzbar
Lagerung -20 °C
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 image for N-Formyl-Met-Leu-Phe peptide (ABIN399635) N-Formyl-Met-Leu-Phe peptide
Produkt verwendet in: van den Broek, Kroeze, Waaijman, Breetveld, Sampat-Sardjoepersad, Niessen, Middelkoop, Scheper, Gibbs: "Differential response of human adipose tissue-derived mesenchymal stem cells, dermal fibroblasts, and keratinocytes to burn wound exudates: potential role of skin-specific chemokine CCL27." in: Tissue engineering. Part A, Vol. 20, Issue 1-2, pp. 197-209, 2014 (PubMed).