anti-Schwein CDKN1A Antikörper für Immunohistochemistry

Recommended CDKN1A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antikörper
  • p21
  • cip1
  • p16Xic2
  • CCND1
  • sdi1
  • waf1
  • cap20
  • cdkn1
  • mda-6
  • p21cip1
  • CDKN1A
  • si:ch1073-48m5.2
  • Cip1
  • UV96
  • Waf1
  • CAP20
  • CDKN1
  • CIP1
  • MDA-6
  • P21
  • SDI1
  • WAF1
  • p21CIP1
  • CDKI
  • Cdkn1
  • mda6
  • p21Cip1
  • p21WAF
  • cyclin-dependent kinase inhibitor 1A L homeolog
  • cyclin-dependent kinase inhibitor 1
  • cyclin D1
  • cyclin-dependent kinase inhibitor 1A
  • cyclin dependent kinase inhibitor 1A
  • cyclin-dependent kinase inhibitor 1A (P21)
  • cdkn1a.L
  • cki1
  • CCND1
  • cdkn1a
  • CDKN1A
  • Cdkn1a
Epitop
N-Term
50
40
40
27
20
20
18
18
18
18
15
15
15
15
12
9
8
7
7
5
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch (Danio rerio)
576
181
121
31
23
8
5
4
3
2
1
1
1
1
Wirt
Kaninchen
310
307
2
1
Klonalität
Polyklonal
Konjugat
Dieser CDKN1A Antikörper ist unkonjugiert
33
32
32
23
23
16
16
15
12
12
10
10
10
10
10
10
10
8
6
6
6
6
4
4
4
4
4
4
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
354
223
187
167
147
140
67
60
58
53
31
14
7
6
6
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2779298
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN602087 IHC Rabbit IgG pThr145 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1836770 IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) Antikörper
Epitop N-Term
(50), (40), (40), (27), (20), (20), (18), (18), (18), (18), (15), (15), (15), (15), (12), (9), (8), (7), (7), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch (Danio rerio)
(576), (181), (121), (31), (23), (8), (5), (4), (3), (2), (1), (1), (1), (1)
Wirt Kaninchen
(310), (307), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser CDKN1A Antikörper ist unkonjugiert
(33), (32), (32), (23), (23), (16), (16), (15), (12), (12), (10), (10), (10), (10), (10), (10), (10), (8), (6), (6), (6), (6), (4), (4), (4), (4), (4), (4)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(354), (223), (187), (167), (147), (140), (67), (60), (58), (53), (31), (14), (7), (6), (6), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CDKN1A Antikörper

Target Details CDKN1A Anwendungsinformationen Handhabung Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN2182053.
Sequenz KACRRLFGPV DSEQLSRDCD ALMAGCIQEA RERWNFDFVT ETPLEGDFAW
Homologie Cow: 100%, Dog: 92%, Guinea Pig: 92%, Horse: 83%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 100%, Zebrafish: 83%
Produktmerkmale This is a rabbit polyclonal antibody against CDKN1A. It was validated on Western Blot.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDKN1A

Target Details CDKN1A

Produktdetails anti-CDKN1A Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CDKN1A (CDKN1A Antibody Abstract)
Hintergrund This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.
Alias Symbols: CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1
Protein Interaction Partner: CCND1, PCNA, KRT31, TRIM54, TEX11, IKZF3, UBC, TRAF1, TCF4, SKP2, CCND3, CCND2, PHKG2, PHKA1, NCL, HSPA9, HSPA8, HSPA5, HSPA2, HSPA1A, HNRNPA2B1, CDK2, CDK5, CDK4, CDK3, CDC20, CCNE1, CCNB1, CCNA2, CAMK2D, ABR, GIGYF2, ANKRD17, UBR4, SNRNP200, FBXO21, PUF
Protein Size: 164
Molekulargewicht 18 kDa
Gen-ID 1026
NCBI Accession NM_078467, NP_510867
UniProt Q6FI05
Pathways p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagie

Anwendungsinformationen

Produktdetails anti-CDKN1A Antikörper Target Details CDKN1A Handhabung Bilder zurück nach oben
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CDKN1A Antikörper Target Details CDKN1A Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeat freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Bilder

Produktdetails anti-CDKN1A Antikörper Target Details CDKN1A Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (N-Term) antibody (ABIN2779298) anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) (N-Term) antibody