anti-Human ATM Antikörper für Immunoprecipitation

Recommended ATM Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Ataxia Telangiectasia Mutated (ATM) Antikörper
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ATM serine/threonine kinase L homeolog
  • ATM serine/threonine kinase
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • serine/threonine-protein kinase ATM
  • tefu
  • atm.L
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • LOC5565620
  • MGYG_07634
  • PGTG_14279
  • Atm
Epitop
full length
89
35
17
17
16
16
10
7
6
6
6
6
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Affe, Maus, Ratte (Rattus)
360
159
81
28
8
1
1
1
1
Wirt
Maus
235
104
13
8
3
1
Klonalität
Monoklonal
Konjugat
Dieser ATM Antikörper ist unkonjugiert
12
11
9
8
8
6
5
5
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
226
143
115
85
82
63
55
44
27
22
13
9
4
4
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN151775
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN151030 ICC FACS IF IHC (p) IP IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 77
1 ABIN151739 IP PLA WB Goat IgG AA 2550-2600 Anmelden zum Anzeigen Polyclonal 4
1 ABIN151622 ICC IF IHC IP WB Mouse IgG1 Anmelden zum Anzeigen 5C2 26
1 ABIN151772 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa pSer1981 Anmelden zum Anzeigen 10H11-E12 20
1 ABIN152102 ICC IF IHC (p) IP IHC PLA WB Rabbit AA 2550-2600 Anmelden zum Anzeigen Polyclonal 2
1 ABIN151738 IP WB Goat IgG AA 1750-1800 Anmelden zum Anzeigen Polyclonal 2
1 ABIN5499238 IHC IHC (p) IP WB Mouse IgG1 AA 980-1512 Anmelden zum Anzeigen 3E8 0
1 ABIN363380 ICC FACS IF IP IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5611379 IHC (p) IP WB Mouse IgG1 AA 980-1512 Anmelden zum Anzeigen 3-00E-008 0
1 ABIN331236 IP ELISA WB Mouse IgG2b, kappa Anmelden zum Anzeigen 0
1 ABIN331246 IP ELISA WB Mouse IgG2b, kappa Anmelden zum Anzeigen 0
1 ABIN153318 IP Agarose Beads Goat IgG AA 2550-2600 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2469773 IP IHC WB Mouse IgG1 AA 980-1152 Anmelden zum Anzeigen 3-00E-008 0
1 ABIN223482 IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5499237 IF IHC IHC (p) IP WB Mouse IgG1 AA 2577-3056 Anmelden zum Anzeigen 2C1 0
1 ABIN221982 IP WB Mouse IgG Anmelden zum Anzeigen 0
1 ABIN342243 IP WB Mouse IgG1 AA 2577-3056 Anmelden zum Anzeigen 0
1 ABIN341825 IP WB Goat Anmelden zum Anzeigen Polyclonal 0
1 ABIN341826 IP WB Goat Anmelden zum Anzeigen Polyclonal 0
1 ABIN2206259 IC IP WB Mouse IgG1 kappa AA 1974-1988, pSer1981 Anmelden zum Anzeigen 5H48 0

General

Antigen Ataxia Telangiectasia Mutated (ATM) Antikörper
Epitop full length
(89), (35), (17), (17), (16), (16), (10), (7), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Affe, Maus, Ratte (Rattus)
(360), (159), (81), (28), (8), (1), (1), (1), (1)
Wirt Maus
(235), (104), (13), (8), (3), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser ATM Antikörper ist unkonjugiert
(12), (11), (9), (8), (8), (6), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Chromatin Immunoprecipitation (ChIP), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(226), (143), (115), (85), (82), (63), (55), (44), (27), (22), (13), (9), (4), (4), (2), (2), (1), (1), (1)
Pubmed 114 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ATM Antikörper

Target Details ATM Anwendungsinformationen Handhabung Referenzen für anti-ATM Antikörper (ABIN151775) Bilder
Spezifität This antibody recognizes full-length ATM, a 350- kDa nuclear phosphoprotein.
Reinigung Protein G purified
Immunogen Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.
Klon 2C1
Isotyp IgG1

Target Details ATM

Produktdetails anti-ATM Antikörper Anwendungsinformationen Handhabung Referenzen für anti-ATM Antikörper (ABIN151775) Bilder zurück nach oben
Antigen
Andere Bezeichnung ATM (ATM Antibody Abstract)
Hintergrund Gene Symbol: ATM
Molekulargewicht Theoretical MW: 370 kDa
Gen-ID 472
UniProt Q13315
Pathways p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Anwendungsinformationen

Produktdetails anti-ATM Antikörper Target Details ATM Handhabung Referenzen für anti-ATM Antikörper (ABIN151775) Bilder zurück nach oben
Applikations-hinweise Western Blot 1:500-1:3000, Chromatin Immunoprecipitation 1:10 - 1:500, Flow Cytometry, ELISA 1:100 - 1:2000, Immunohistochemistry 10 - 1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1-10 μg/mL, Immunohistochemistry-Paraffin 5 μg/mLIHC-R. ICC/IF usage reported in scientifc literature (Harry Scherthan, et.al., 2000 and Yiyoung Liu, et.al., 2006). ELISA usage reported in scientific literature. WB: Predicted molecular weight: 350 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ATM Antikörper Target Details ATM Anwendungsinformationen Referenzen für anti-ATM Antikörper (ABIN151775) Bilder zurück nach oben
Format Liquid
Konzentration 1.85 mg/mL
Buffer PBS ( pH 7.4)
Buffer contains: No Preservative
Konservierungs-mittel Without preservative
Handhabung Avoid freeze-thaw cycles
Lagerung -80 °C,-20 °C
Informationen zur Lagerung Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Referenzen für anti-ATM Antikörper (ABIN151775)

Produktdetails anti-ATM Antikörper Target Details ATM Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Simões, Martins, Ferreira: "Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus." in: Virus research, Vol. 210, pp. 1-7, 2015

Park, Kong, Kim, Lee, Park: "Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest." in: American journal of cancer research, Vol. 5, Issue 7, pp. 2127-38, 2015 Weitere Details: Western Blotting

Batenburg, Thompson, Hendrickson, Zhu: "Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation." in: The EMBO journal, Vol. 34, Issue 10, pp. 1399-416, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Vermezovic, Adamowicz, Santarpia, Rustighi, Forcato, Lucano, Massimiliano, Costanzo, Bicciato, Del Sal, dAdda di Fagagna: "Notch is a direct negative regulator of the DNA-damage response." in: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 417-24, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Muraki, Han, Miller, Murnane: "Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks." in: Nucleic acids research, Vol. 43, Issue 16, pp. 7911-30, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting

Gutiérrez-González, Belda-Iniesta, Bargiela-Iparraguirre, Dominguez, García Alfonso, Perona, Sanchez-Perez: "Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 3, pp. 347-60, 2013 (Probematerial (Species): Human). Weitere Details: Western Blotting

Min, Bruhn, Grigaravicius, Zhou, Li, Krüger, Siddeek, Greulich, Popp, Meisezahl, Calkhoven, Bürkle, Xu, Wang: "Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation." in: Nature communications, Vol. 4, pp. 2993, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Murad, Cullen, McKenzie, Ryan, Thorburn, Gueven, Kobayashi, Birrell, Yang, Dörk, Becherel, Grattan-Smith, Lavin: "Mitochondrial dysfunction in a novel form of autosomal recessive ataxia." in: Mitochondrion, Vol. 13, Issue 3, pp. 235-45, 2013 (Probematerial (Species): Human). Weitere Details: Western Blotting

Simões, Martins, Ferreira: "Host DNA damage response facilitates African swine fever virus infection." in: Veterinary microbiology, Vol. 165, Issue 1-2, pp. 140-7, 2013

Hao, Duncan, Su, Li, Silvester, Hong, You, Brenner, Gorrini, Haight, Wakeham, You-Ten, McCracken, Elia, Li, Detmar, Jurisicova, Hobeika, Reth, Sheng, Lang, Ohashi, Zhong, Wang, Mak: "The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis." in: The Journal of experimental medicine, Vol. 209, Issue 1, pp. 173-86, 2012

Kang, So, Ouchi: "Deregulation of DNA damage response pathway by intercellular contact." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16246-55, 2012 Weitere Details: Western Blotting

Zhang, de Toledo, Pandey, Guo, Pain, Li, Azzam: "Role of the translationally controlled tumor protein in DNA damage sensing and repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. E926-33, 2012

Ai, Skehan, Saydi, Lin, Brown: "Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression." in: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 18330-41, 2012 (Probematerial (Species): Human). Weitere Details: ELISA

Yan, Greer, Cao, Kolb, Cowan: "RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation." in: Breast cancer research : BCR, Vol. 14, Issue 2, pp. R60, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting

Hsu, Lee, Yeh, Chen, Wu, Wang, Chen, Hung, Liu, Chen, Hsiao, Wang, Tsou, Tsou, Wu, Chang, Lin: "58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway." in: The Journal of biological chemistry, Vol. 287, Issue 27, pp. 22533-48, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting

Mahajan, Coppola, Rawal, Chen, Lawrence, Engelman, Lawrence, Mahajan: "Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 26, pp. 22112-22, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting

Hardee, Marciscano, Medina-Ramirez, Zagzag, Narayana, Lonning, Barcellos-Hoff: "Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β." in: Cancer research, Vol. 72, Issue 16, pp. 4119-29, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting

Baritaud, Cabon, Delavallée, Galán-Malo, Gilles, Brunelle-Navas, Susin: "AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation." in: Cell death & disease, Vol. 3, pp. e390, 2012 Weitere Details: Western Blotting

Shi, Felley-Bosco, Marti, Stahel: "Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy." in: PLoS ONE, Vol. 7, Issue 9, pp. e45354, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting

Sakasai, Sakai, Iimori, Kiyonari, Matsuoka, Kakeji, Kitao, Maehara: "CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 12, pp. 962-70, 2012 (Probematerial (Species): Human). Weitere Details: Western Blotting

Bilder

Produktdetails anti-ATM Antikörper Target Details ATM Anwendungsinformationen Handhabung Referenzen für anti-ATM Antikörper (ABIN151775) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Detection of ATM (Anti-ATM 2C1, ABIN151775) or ATR by western blot in human Raji whol...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug U87-MG whole cell lysate/ext...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - A. 30 ug NT2D1 whole cell lysate/extr...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Western Blot: ATM Antibody (2C1) [ABIN151775] - analysis of ATM in U2OS sarcoma cells...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Testis (formal...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ataxia Telangiectasia Mutated (ATM) (full length) antibody (ABIN151775) Immunohistochemistry-Paraffin: ATM Antibody (2C1) [ABIN151775] - Human Kidney (formal...