NXF1 Produkte
(Nuclear RNA Export Factor 1 (NXF1))
Kategorien
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].
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Ausgewählte NXF1 Kategorien
NXF1 Antikörper
High quality antibodies with extensive validation data.
NXF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NXF1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NXF1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6263783
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN2855276
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ICC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN2855280
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NXF1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1116233
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN511451
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Goat
Analytical Method
Competition ELISA
Validierungen
Kat. Nr.
ABIN995473
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NXF1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1313263
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124215
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313265
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NXF1 Produkten
: "Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the cellular NXF1-p15 machinery." in: PLoS ONE, Vol. 9, Issue 10, pp. e106683, (2014) (PubMed).: "Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs." in: Molecular and cellular biology, Vol. 19, Issue 9, pp. 6306-17, (1999) (PubMed).
: "TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus." in: The EMBO journal, Vol. 18, Issue 7, pp. 1953-65, (1999) (PubMed).
: "Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation." in: Immunity, Vol. 6, Issue 5, pp. 571-82, (1997) (PubMed).
Synonyme und alternative Namen zu NXF1
nuclear RNA export factor 1 (nxf1), nuclear RNA export factor 1 S homeolog (nxf1.S), nuclear RNA export factor 1 (NXF1), nuclear RNA export factor 1 (LOC100113601), nuclear RNA export factor 1 (Tsp_03999), nuclear RNA export factor 1 (Nxf1), Nuclear RNA export factor 1 (nxf-1), im:7156527, mex67, MEX67, Mex67, Mex67h, MGC82224, Mvb1, NXF1, tap, TAP, Tap, wu:fc12d06Bezeichner auf Proteinebene für NXF1
- nuclear RNA export factor 1
- small bristles
- Nuclear RNA export factor 1
- nuclear RNA export factor 1-like
- mRNA export factor TAP
- tip associating protein
- tip-associated protein
- tip-associating protein
- Mex 67 homolog
- modifier of vibrator 1
- nuclear RNA export factor 1 homolog
- tip associated protein
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