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a Gbetagamma-activated AC is playing an important role in Xenopus oocyte meiotic arrest in a Galphas (zeige GNAS ELISA Kits)-GTP (zeige AK3 ELISA Kits) dependent manner.
AK7 may be involved in the development of Primary ciliary dyskinesia (PCD (zeige Dnah5 ELISA Kits)).
Both AK7 and full-length AK8 (zeige AK8 ELISA Kits) showed highest affinity for AMP (zeige APRT ELISA Kits) with ATP as the phosphate donor, and proved to be more efficient in AMP (zeige APRT ELISA Kits) phosphorylation as compared with the major cytosolic isoform AK1 (zeige AK1 ELISA Kits)
Data show that a mutation of the adenylate kinase 7 gene results in animals with pathological signs characteristic of primary ciliary dyskinesia, including ultrastructural ciliary defects and decreased ciliary beat frequency in respiratory epithelium.
Adenylate kinase involved in maintaining ciliary structure and function (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP.
putative adenylate kinase 7
, adenylate kinase 7
, putative adenylate kinase 7-like
, ATP-AMP transphosphorylase 7