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this study identified a novel regulatory circuit for ovarian AMH (zeige AMH Proteine) production; specifically, through the coordinated interplay between FOXL2 (zeige FOXL2 Proteine) and SF-1 (zeige NR5A1 Proteine) that could control ovarian follicle development.
SF1 Phosphorylation Enhances Specific Binding to U2AF(65) and Reduces Binding to 3'-Splice-Site RNA
SF1 (zeige NR5A1 Proteine) was the only specific marker of uterine tumour resembling ovarian sex cord-stromal tumour
rete ovarii were positive for PAX-8 (zeige PAX8 Proteine), weakly positive for SF-1 (zeige NR5A1 Proteine), and negative for PAX-2 (zeige PAX2 Proteine) and GATA-3 (zeige GATA3 Proteine)
A novel function of SF1 (zeige NR5A1 Proteine) in the initial recruitment of the U2 snRNP (zeige LSM2 Proteine) through direct interactions with two U2 snRNP (zeige LSM2 Proteine)-associated proteins.
Data suggest that post-translational processing of SF1 (zeige NR5A1 Proteine) (phosphorylation of Ser20) down-regulates nuclear import of SF1 (zeige NR5A1 Proteine) via alterations in kinetic interaction of SF1 (zeige NR5A1 Proteine) nuclear localization signal (NLS (zeige ALDH1A2 Proteine)) with NLS (zeige ALDH1A2 Proteine) receptor isoforms.
We demonstrated that PRPF40B interacts directly with SF1 and associates with U2AF(65
Gomafu indirectly modulates the function of the splicing factors SF1 (zeige NR5A1 Proteine) and Celf3 (zeige CELF3 Proteine) by sequestering these proteins into separate nuclear bodies.
The conserved SPSP motif phosphorylation and the SF1 (zeige NR5A1 Proteine)/U2AF interface are essential in vivo.
Findings suggest that Zinc finger motif-1 (ZFM1) is an important factor for the stabilization of a contractile SMC (zeige DYM Proteine) phenotype under basal or mildly activating conditions.
SF1 directly contributes to the abnormal uterine gland morphogenesis.
Sf1 SUMOylation and Dax1 (zeige NR0B1 Proteine) have roles in the physiological cessation of FAdE-mediated Sf1 expression and the resultant regression of the postnatal fetal cortex (X-zone)
we found that KLF6 (zeige KLF6 Proteine) transcriptionally cooperates with NUR77 (zeige NR4A1 Proteine) and SF1
SF1 in the ventromedial nucleus of the hypothalamus regulates age-dependent obesity.
Data suggest that Sf1 and c-jun interact and cooperate to activate the Fdx1 promoter in MA-10 (tumorigenic cell line) and TM3 (non-tumorigenic cell line) Leydig cells; such activation requires different regulatory elements located between -124 and -306 bp of Fdx1 promoter and involves recruitment of Sf1 to this region. (Sf1 = splicing factor 1; c-jun = proto-oncogene c-jun; Fdx1 = ferredoxin 1)
The results of the current study show that EB treatment from P25 (zeige CDK5R1 Proteine) to P36 (zeige ANXA2 Proteine) could not restore the number of kisspeptin-ir cells in the AVPV in agonadal SF-1 KO mice to numbers found in gonadally intact WT or EB-treated WT/OVX females
the data suggest that the inhibitory effects of melatonin on testosterone production are mediated via down-regulation of GATA-4 (zeige GATA4 Proteine) and SF-1 expression.
Results clearly indicate that SF-1 is involved in the regulation of LIPE (zeige LIPE Proteine) expression after activation of protein kinase A in adrenocortical cells.
SF-1 is involved in cell cycle regulation, neurogenesis, and neuronal migration via controlling the estrogen signaling for proper neocortical development.
SIRT1 (zeige SIRT1 Proteine) Relays Nutritional Inputs to the Circadian Clock Through the Sf1 Neurons of the Ventromedial Hypothalamus.
The studies performed did not confirm the ability of the SF1 insulator to protect expression of reporter gene white from the chromosome position effect in transgenic lines.
RRM domain of Arabidopsis splicing factor (zeige SLU7 Proteine) SF1 is important for pre-mRNA splicing of a specific set of genes
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants.
mammalian branch point-binding protein
, transcription factor ZFM1
, zinc finger gene in MEN1 locus
, zinc finger protein 162
, splicing factor 1
, splicing factor 1, isoform 1