anti-Ratte (Rattus) Progesterone Receptor Antikörper für Immunohistochemistry (Frozen Sections)

Recommended Progesterone Receptor Antibody

Antigen
Progesterone Receptor (PGR) Antikörper
  • NR3C3
  • PR
  • 9930019P03Rik
  • BB114106
  • ENSMUSG00000074510
  • PR-A
  • PR-B
  • XPR-1
  • pgr
  • xpr-2
  • LOC443444
  • PGR
  • pg
  • pr
  • gb:dq017620
  • progesterone receptor
  • progesterone receptor L homeolog
  • PGR
  • Pgr
  • pgr.L
  • pgr
Epitop
pSer294
53
49
41
27
25
23
19
18
17
17
15
15
11
10
10
9
9
8
8
8
7
7
7
7
5
5
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Non-Human Primate, Ratte (Rattus)
667
114
109
25
10
9
7
6
5
3
3
3
2
2
1
1
1
Wirt
Maus
387
291
3
1
Klonalität
Monoklonal
Konjugat
Dieser Progesterone Receptor Antikörper ist unkonjugiert
29
17
16
12
12
12
11
11
11
11
11
11
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
457
198
166
129
93
67
50
28
26
20
19
9
3
2
2
1
1
1
Optionen
Produktnummer ABIN5550817
$ 511.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
1 ABIN209187 ICC IHC IHC (fro) IHC (p) IP WB Mouse IgG2a 0
-5.610054 ABIN266931 ICC IHC (fro) IF IHC (p) IP IHC WB Mouse IgG2a B form Alpha PR6 1
-13.110054 ABIN4347450 ICC IF IHC (fro) IHC (p) WB DyLight 350 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347452 ICC IF IHC (fro) IHC (p) WB DyLight 405 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347459 ICC IF IHC (fro) IHC (p) WB DyLight 755 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347461 ICC IF IHC (fro) IHC (p) WB DyLight 488 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347465 ICC IF IHC (fro) IHC (p) WB DyLight 680 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347467 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 405 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347469 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347471 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 647 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN4347473 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 700 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN5946888 ICC IF IHC IHC (fro) IHC (p) Janelia Fluor® 646 Mouse IgG2a B form Alpha PR6 0
-13.110054 ABIN5946887 ICC IF IHC IHC (fro) IHC (p) Janelia Fluor® 549 Mouse IgG2a B form Alpha PR6 0

General

Antigen Progesterone Receptor (PGR) Antikörper
Epitop pSer294
(53), (49), (41), (27), (25), (23), (19), (18), (17), (17), (15), (15), (11), (10), (10), (9), (9), (8), (8), (8), (7), (7), (7), (7), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Non-Human Primate, Ratte (Rattus)
(667), (114), (109), (25), (10), (9), (7), (6), (5), (3), (3), (3), (2), (2), (1), (1), (1)
Wirt Maus
(387), (291), (3), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Progesterone Receptor Antikörper ist unkonjugiert
(29), (17), (16), (12), (12), (12), (11), (11), (11), (11), (11), (11), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(457), (198), (166), (129), (93), (67), (50), (28), (26), (20), (19), (9), (3), (2), (2), (1), (1), (1)
Hersteller

Produktdetails anti-Progesterone Receptor Antikörper

Target Details Progesterone Receptor Anwendungsinformationen Handhabung Bilder
Spezifität This antibody is specific for the ~90k PR-A isoform and the ~120k PR-B isoform phosphorylated at Ser294. Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide.
Kreuzreaktivität (Details) Species reactivity (expected):Mouse, Rat and non-Human Primates.
Species reactivity (tested):Human.
Produktmerkmale Synonyms: PR, PGR, NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3
Reinigung Affinity Chromatography on Protein G.
Immunogen Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser294of Human progesterone receptor.
Klon 608
Isotyp IgG1
Plasmids, Primers & others

Target Details Progesterone Receptor

Produktdetails anti-Progesterone Receptor Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Progesterone Receptor (PGR Antibody Abstract)
Hintergrund There is accumulating evidence to suggest that progesterone plays an essential role in the regulation of growth and differentiation of mammary glands and thus may play a key role in breast cancer (Edwards, 2005). The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (PR-A and PR-B forms). In most cell contexts, the B form functions as a transcriptional activator, whereas the A form functions as a transcriptional inhibitor of steroid hormones (Attia et al., 2000, Lin et al., 2003). Recently it has been demonstrated that there is differential hormone dependent regulation of the phosphorylation of the A and B forms of the receptor (Clemm et al., 2000) . Treatment of T47D breast cancer cells with progestin agonist increases the phosphorylation of Ser190 and Ser294 with different kinetics. These phosphorylation events may differentially affect the transcriptional activity of the receptor.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Gen-ID 5241
UniProt P06401
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-Progesterone Receptor Antikörper Target Details Progesterone Receptor Handhabung Bilder zurück nach oben
Applikations-hinweise Western Blot: 1/1000. Immunohistochemitry (Frozen Sections, unpublished observations): 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Progesterone Receptor Antikörper Target Details Progesterone Receptor Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Lagerung -20 °C
Informationen zur Lagerung Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months