anti-Kaninchen Progesterone Receptor Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended Progesterone Receptor Antibody

Antigen
Progesterone Receptor (PGR) Antikörper
  • NR3C3
  • PR
  • 9930019P03Rik
  • BB114106
  • ENSMUSG00000074510
  • PR-A
  • PR-B
  • XPR-1
  • pgr
  • xpr-2
  • LOC443444
  • PGR
  • pg
  • pr
  • gb:dq017620
  • progesterone receptor
  • progesterone receptor L homeolog
  • PGR
  • Pgr
  • pgr.L
  • pgr
Epitop
AA 922-933, C-Term
53
48
45
38
27
25
21
19
18
16
16
15
12
11
10
10
9
9
8
8
8
7
7
6
6
5
5
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Huhn, Human, Kaninchen
711
158
155
25
10
8
6
6
5
3
3
3
2
2
1
1
1
1
Wirt
Maus
425
295
3
1
Klonalität
Monoklonal
Konjugat
Dieser Progesterone Receptor Antikörper ist unkonjugiert
31
20
18
14
14
14
14
14
14
12
12
12
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
459
208
163
136
93
67
67
50
26
20
18
10
9
3
2
2
1
1
1
Optionen

Bilder

Produktnummer ABIN781660
$ 511.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
1 ABIN209187 ICC IHC IHC (fro) IHC (p) IP WB Mouse IgG2a 0
-0.82387495 ABIN266931 ICC IHC (fro) IF IHC (p) IP IHC WB Mouse IgG2a B form Alpha PR6 1
-13.184835 ABIN4347450 ICC IF IHC (fro) IHC (p) WB DyLight 350 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347452 ICC IF IHC (fro) IHC (p) WB DyLight 405 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347459 ICC IF IHC (fro) IHC (p) WB DyLight 755 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347461 ICC IF IHC (fro) IHC (p) WB DyLight 488 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347465 ICC IF IHC (fro) IHC (p) WB DyLight 680 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347467 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 405 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347469 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347471 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 647 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN4347473 ICC IF IHC (fro) IHC (p) WB Alexa Fluor 700 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN5946888 ICC IF IHC IHC (fro) IHC (p) Janelia Fluor® 646 Mouse IgG2a B form Alpha PR6 0
-13.184835 ABIN5946887 ICC IF IHC IHC (fro) IHC (p) Janelia Fluor® 549 Mouse IgG2a B form Alpha PR6 0

General

Antigen Progesterone Receptor (PGR) Antikörper
Epitop AA 922-933, C-Term
(53), (48), (45), (38), (27), (25), (21), (19), (18), (16), (16), (15), (12), (11), (10), (10), (9), (9), (8), (8), (8), (7), (7), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Huhn, Human, Kaninchen
(711), (158), (155), (25), (10), (8), (6), (6), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Wirt Maus
(425), (295), (3), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Progesterone Receptor Antikörper ist unkonjugiert
(31), (20), (18), (14), (14), (14), (14), (14), (14), (12), (12), (12), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(459), (208), (163), (136), (93), (67), (67), (50), (26), (20), (18), (10), (9), (3), (2), (2), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller

Produktdetails anti-Progesterone Receptor Antikörper

Target Details Progesterone Receptor Anwendungsinformationen Handhabung Referenzen für anti-Progesterone Receptor Antikörper (ABIN781660) Bilder
Spezifität This antibody PR-6A recognizes the Human Progesterone Receptor in the C-terminal ligand-binding domain. Therefore, it recognizes isoforms A and B. Antigen Distribution: Nuclear hormone receptor, widely expressed.
Kreuzreaktivität (Details) Species reactivity (expected):Chicken and Rabbit.
Species reactivity (tested):Human, Pig.
Reinigung Affinity Chromatography
Immunogen Peptide A922-K933. Epitope: C-terminal region.
Klon PR-6A
Isotyp IgG2a
Plasmids, Primers & others

Target Details Progesterone Receptor

Produktdetails anti-Progesterone Receptor Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Progesterone Receptor Antikörper (ABIN781660) Bilder zurück nach oben
Antigen
Andere Bezeichnung Progesterone Receptor (PGR Antibody Abstract)
Hintergrund The progesterone receptor is an intracellular steroid receptor that specifically binds progesterone. Expressed by a single gene (chromosome 11q22), it has two main forms, A and B, that differ in their molecular weight. It has been proposed that expression of PR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PR determination provides supplementary information to ER, in predicting response to endocrine therapy as well as estimating survival. PR has proved superior to ER as a prognostic indicator in some studies. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Gen-ID 5241
NCBI Accession NP_000917
UniProt P06401
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration

Anwendungsinformationen

Produktdetails anti-Progesterone Receptor Antikörper Target Details Progesterone Receptor Handhabung Referenzen für anti-Progesterone Receptor Antikörper (ABIN781660) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Progesterone Receptor Antikörper Target Details Progesterone Receptor Anwendungsinformationen Referenzen für anti-Progesterone Receptor Antikörper (ABIN781660) Bilder zurück nach oben
Rekonstitution Restore by adding 0.5 mL distilled water
Konzentration 0.2 mg/mL
Buffer Stock solution contains PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.01 % Kathon as a preservative.
Konservierungs-mittel Kathon CG
Vorsichtsmaßnahmen This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Progesterone Receptor Antikörper (ABIN781660)

Produktdetails anti-Progesterone Receptor Antikörper Target Details Progesterone Receptor Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lee, Dai, Hansen, Saner, Price: "Modulation of ATP-induced calcium signaling by progesterone in T47D-Y breast cancer cells." in: Molecular and cellular endocrinology, Vol. 319, Issue 1-2, pp. 109-15, 2010

Tetel, Siegal, Murphy: "Cells in behaviourally relevant brain regions coexpress nuclear receptor coactivators and ovarian steroid receptors." in: Journal of neuroendocrinology, Vol. 19, Issue 4, pp. 262-71, 2007

Price, Hansen, Oliver: "Immunofluorescent localization of a novel progesterone receptor(s) in a T47D-Y breast cancer cell line lacking genomic progesterone receptor expression." in: Journal of the Society for Gynecologic Investigation, Vol. 12, Issue 8, pp. 610-6, 2005

Bennett, Gréco, Blasberg, Blaustein: "Response to male odours in progestin receptor- and oestrogen receptor-containing cells in female rat brain." in: Journal of neuroendocrinology, Vol. 14, Issue 6, pp. 442-9, 2002

Frye: "The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents." in: Brain research. Brain research reviews, Vol. 37, Issue 1-3, pp. 201-22, 2001

Bilder

Produktdetails anti-Progesterone Receptor Antikörper Target Details Progesterone Receptor Anwendungsinformationen Handhabung Referenzen für anti-Progesterone Receptor Antikörper (ABIN781660) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody (ABIN781660) anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody
Immunohistochemistry (IHC) image for anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody (ABIN781660) anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody (ABIN781660) anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody (Image 3)