anti-Schaf Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antikörper für Neutralization

Recommended Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibody

Antigen
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antikörper
  • GR
  • gcr
  • grl
  • xGR
  • gccr
  • gr
  • zgc:113038
  • NR3C1
  • GCL
  • LOC100302444
  • Gcr
  • Grl
  • Grl-1
  • Grl1
  • GRL
  • GCCR
  • GCR
  • NO
  • GR-A
  • nr3c1
  • nuclear receptor subfamily 3 group C member 1
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
  • nuclear receptor subfamily 3, group C, member 1
  • glucocorticoid receptor
  • NR3C1
  • nr3c1
  • LOC100302444
  • Nr3c1
Reaktivität
Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus), Schaf, Yeast (Saccharomyces cerevisiae)
299
156
139
8
7
6
5
5
4
4
3
1
1
1
Wirt
Maus
258
59
5
Klonalität
Monoklonal
Konjugat
Unkonjugiert
23
20
10
7
6
6
6
6
6
6
6
6
3
3
3
3
3
1
1
Applikation
Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Flow Cytometry (FACS), Gel Shift (GS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
236
124
107
64
56
39
36
29
27
18
4
3
2
1
1
Optionen

Bilder

Produktnummer ABIN268501
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
-13.110054 ABIN4315958 BP ChIP FACS GS ICC IF IHC IHC (p) IP Neut WB PerCP Mouse IgG2 BuGR2 0

General

Antigen Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antikörper
Reaktivität Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus), Schaf, Yeast (Saccharomyces cerevisiae)
(299), (156), (139), (8), (7), (6), (5), (5), (4), (4), (3), (1), (1), (1)
Wirt Maus
(258), (59), (5)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(23), (20), (10), (7), (6), (6), (6), (6), (6), (6), (6), (6), (3), (3), (3), (3), (3), (1), (1)
Applikation Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Flow Cytometry (FACS), Gel Shift (GS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
(236), (124), (107), (64), (56), (39), (36), (29), (27), (18), (4), (3), (2), (1), (1)
Pubmed 8 Publikationen vorhanden
Hersteller

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität Using enzymatic digestion analysis, has been shown to react with the undigested 97 kDa GR, a 17 kDa DNA-binding trypsin fragment, and a 45 kDa steroid- and DNA-binding chymotrypsin fragment.
Reinigung Protein A purified
Immunogen Partially purified rat GR.
Klon BuGR2
Isotyp IgG2

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung GR/NR3C1 (NR3C1 Antibody Abstract)
Hintergrund Gene Symbol: NR3C1
Gen-ID 2908
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikations-hinweise Western Blot 5 μg/mL, Chromatin Immunoprecipitation 1:10 - 1:500, Flow Cytometry 1:10 - 1:1000, Immunohistochemistry 1:10 - 1:500, Immunocytochemistry/Immunofluorescence 1:10 - 1:500, Immunoprecipitation 1:10 - 1:500, Immunohistochemistry-Paraffin 5 μg/mL, Gel Super Shift Assays 1:1- 1:100, Blocking/Neutralizing 50 - 200 Molar excessBlocking, ChIP, and ELISA usages were reported in scientific literature.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Lyophilized
Rekonstitution Reconstitute with 0.1 mL sterilized water to desired concentration.
Buffer PBS ( pH 7.2)
Buffer contains: 0.05 % Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Taves, Mittelstadt, Presman, Hager, Ashwell: "Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus." in: Cell reports, Vol. 26, Issue 13, pp. 3629-3642.e4, 2019 (Probematerial (Species): Mouse (Murine)).

Rué, Bañez-Coronel, Creus-Muncunill, Giralt, Alcalá-Vida, Mentxaka, Kagerbauer, Zomeño-Abellán, Aranda, Venturi, Pérez-Navarro, Estivill, Martí: "Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels." in: The Journal of clinical investigation, Vol. 126, Issue 11, pp. 4319-4330, 2016

Wu, Pinello, Yissachar, Wischhusen, Yuan, Roberts: "Functionally distinct patterns of nucleosome remodeling at enhancers in glucocorticoid-treated acute lymphoblastic leukemia." in: Epigenetics & chromatin, Vol. 8, pp. 53, 2015 Weitere Details: Chromatin Immunoprecipitation

Schoenfelder, Hiemke, Schmitt: "Behavioural consequences of p-glycoprotein deficiency in mice, with special focus on stress-related mechanisms." in: Journal of neuroendocrinology, Vol. 24, Issue 5, pp. 809-17, 2012 (Probematerial (Species): Mouse (Murine)).

Viegas, Vicent, Barañao, Beato, Pecci: "Steroid hormones induce bcl-X gene expression through direct activation of distal promoter P4." in: The Journal of biological chemistry, Vol. 279, Issue 11, pp. 9831-9, 2004

Harrell, Murphy, Morishima, Chen, Mansfield, Galigniana, Pratt: "Evidence for glucocorticoid receptor transport on microtubules by dynein." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54647-54, 2004

Lambert, Nordeen: "CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins." in: Molecular endocrinology (Baltimore, Md.), Vol. 17, Issue 6, pp. 1085-94, 2003

Hutchison, Dittmar, Pratt et al.: "All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with heat shock protein 90 are preassociated in a self-sufficient protein folding structure, a ..." in: The Journal of biological chemistry, Vol. 269, Issue 45, pp. 27894-9, 1994

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Immunofluorescence (IF) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Immunocytochemistry/Immunofluorescence: GR/NR3C1 Antibody (BuGR2) [ABIN268501] - Anal...
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Western Blot: GR/NR3C1 Antibody (BuGR2) [ABIN268501] - Analysis of glucocorticoid rec...
Immunofluorescence (IF) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Immunocytochemistry/Immunofluorescence: GR/NR3C1 Antibody (BuGR2) [ABIN268501] - Anal...
Immunofluorescence (IF) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Immunocytochemistry/Immunofluorescence: GR/NR3C1 Antibody (BuGR2) [ABIN268501] - Anal...
Flow Cytometry (FACS) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Flow Cytometry: GR/NR3C1 Antibody (BuGR2) [ABIN268501] - Analysis of Glucocorticoid R...
Flow Cytometry (FACS) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Flow Cytometry: GR/NR3C1 Antibody (BuGR2) [ABIN268501] - Analysis of Glucocorticoid R...
Flow Cytometry (FACS) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Flow Cytometry: GR/NR3C1 Antibody (BuGR2) [ABIN268501] - Analysis of GR in Jurkat cel...
Flow Cytometry (FACS) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Flow Cytometry: GR/NR3C1 Antibody (BuGR2) - Using the Alexa Fluor 647 direct conjuga...
Flow Cytometry (FACS) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) antibody (ABIN268501) Flow Cytometry: GR/NR3C1 Antibody (BuGR2) - An intracellular stain was performed on ...