anti-Human Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibody

Antigen
Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antikörper
  • GR
  • gcr
  • grl
  • xGR
  • gccr
  • gr
  • zgc:113038
  • NR3C1
  • GCL
  • LOC100302444
  • Gcr
  • Grl
  • Grl-1
  • Grl1
  • GRL
  • GCCR
  • GCR
  • NO
  • GR-A
  • nr3c1
  • nuclear receptor subfamily 3 group C member 1
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
  • nuclear receptor subfamily 3, group C, member 1
  • glucocorticoid receptor
  • NR3C1
  • nr3c1
  • LOC100302444
  • Nr3c1
Epitop
AA 230-280
26
25
21
18
18
15
13
11
10
10
7
7
7
7
5
5
5
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
298
155
138
8
7
6
5
5
4
4
3
1
1
1
Wirt
Kaninchen
257
59
5
Klonalität
Polyklonal
Konjugat
Unkonjugiert
23
20
10
7
6
6
6
6
6
6
6
6
3
3
3
3
3
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
235
124
107
64
55
38
35
29
27
18
4
3
2
1
1
Optionen

Bilder

Produktnummer ABIN726875
$ 329.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
11.5 ABIN685138 IF (p) IHC (p) WB Rabbit IgG pSer211 Polyclonal 1
8.5 ABIN1713964 IF (p) IHC (p) WB Rabbit IgG pSer226 Polyclonal 1
1 ABIN1705897 IF (p) Cy5.5 Rabbit IgG pSer226 Polyclonal 0
1 ABIN1709666 IF (p) FITC Rabbit IgG pSer226 Polyclonal 0
1 ABIN1707855 IF (p) Cy7 Rabbit IgG pSer226 Polyclonal 0
1 ABIN1695011 IF (p) Alexa Fluor 488 Rabbit IgG pSer226 Polyclonal 0
1 ABIN1696838 IF (p) Alexa Fluor 555 Rabbit IgG pSer226 Polyclonal 0
1 ABIN1702275 IF (p) Cy3 Rabbit IgG pSer226 Polyclonal 0
1 ABIN1704086 IF (p) Cy5 Rabbit IgG pSer226 Polyclonal 0
1 ABIN1698649 IF (p) Alexa Fluor 647 Rabbit IgG pSer226 Polyclonal 0
1 ABIN1693195 IF (p) Alexa Fluor 350 Rabbit IgG pSer226 Polyclonal 0
1 ABIN899042 FACS IF (p) Alexa Fluor 647 Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN899038 FACS IF (p) Alexa Fluor 488 Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN899039 FACS IF (p) Alexa Fluor 350 Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN899040 FACS IF (p) Alexa Fluor 555 Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN726880 FACS IF (p) Cy5.5 Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN726881 FACS IF (p) Cy7 Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN726878 FACS IF (p) Cy3 Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN726882 FACS IF (p) FITC Rabbit IgG AA 230-280 Polyclonal 0
1 ABIN726879 FACS IF (p) Cy5 Rabbit IgG AA 230-280 Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antikörper
Epitop AA 230-280
(26), (25), (21), (18), (18), (15), (13), (11), (10), (10), (7), (7), (7), (7), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(298), (155), (138), (8), (7), (6), (5), (5), (4), (4), (3), (1), (1), (1)
Wirt Kaninchen
(257), (59), (5)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(23), (20), (10), (7), (6), (6), (6), (6), (6), (6), (6), (6), (3), (3), (3), (3), (3), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(235), (124), (107), (64), (55), (38), (35), (29), (27), (18), (4), (3), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Glucocorticoid receptor
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung Glucocorticoid Receptor (NR3C1 Antibody Abstract)
Hintergrund

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.

Subcellular location: Cytoplasm, Nucleus

Synonyms: GR, GCR, GRL, GCCR, GCRST, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1, NR3C1

Gen-ID 2908
UniProt P04150
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process

Anwendungsinformationen

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Applikations-hinweise WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen

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Produkt verwendet in:

Takigawa, Miyazaki, Kinoshita, Kawarabayashi, Nishiyama, Hatsuse, Ono, Saitoh, Seki, Yamamoto: "Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 305, Issue 6, pp. G427-38, 2013

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Immunofluorescence (IF) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 230-280) antibody (ABIN726875) Formalin-fixed and paraffin embedded: human lung epithelial cells labeled with Anti-G...
Immunofluorescence (IF) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 230-280) antibody (ABIN726875) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-Glucocortico...
ELISA image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 230-280) antibody (ABIN726875) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...
Flow Cytometry (FACS) image for anti-Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) (AA 230-280) antibody (ABIN726875) Mouse liver cells probed with Rabbit Anti-Glucocorticoid receptor Polyclonal Antibody...