anti-Human Nuclear Receptor Subfamily 1, Group I, Member 2 Antikörper für Enzyme Immunoassay

Recommended Nuclear Receptor Subfamily 1, Group I, Member 2 Antibody

Antigen
Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) Antikörper
  • BXR
  • ONR1
  • PAR
  • PAR1
  • PAR2
  • PARq
  • PRR
  • PXR
  • SAR
  • SXR
  • PXR.1
  • PXR.2
  • PXR1
  • mPXR
  • bxr
  • nr1i2
  • onr1
  • xonr1
  • nuclear receptor subfamily 1 group I member 2
  • nuclear receptor subfamily 1, group I, member 2
  • nuclear receptor subfamily 1 group I member 2 S homeolog
  • NR1I2
  • Nr1i2
  • nr1i2.S
  • nr1i2
Epitop
Middle Region
15
15
11
10
9
8
6
6
5
5
3
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human
135
59
58
2
2
2
2
2
1
1
1
Wirt
Kaninchen
120
21
12
Klonalität
Polyklonal
Konjugat
Unkonjugiert
10
9
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
117
58
37
26
17
11
10
10
8
7
2
1
Optionen

Bilder

Produktnummer ABIN453773
$ 484.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
1 ABIN5554075 EIA IHC (p) WB Goat Internal Region Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) Antikörper
Epitop Middle Region
(15), (15), (11), (10), (9), (8), (6), (6), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(135), (59), (58), (2), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(120), (21), (12)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(10), (9), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(117), (58), (37), (26), (17), (11), (10), (10), (8), (7), (2), (1)
Pubmed 1 Publikation vorhanden
Hersteller

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität This antibody reacts to NR1I2.
Reinigung Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide selected from the Center region of human NR1I2

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung NR1I2 (NR1I2 Antibody Abstract)
Hintergrund NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. This protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin.Synonyms: Nuclear receptor subfamily 1 group I member 2, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, PXR, Pregnane X receptor, Steroid and xenobiotic receptor
Gen-ID 8856
NCBI Accession NP_003880
UniProt O75469
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lehmann, McKee, Watson, Willson, Moore, Kliewer: "The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions." in: The Journal of clinical investigation, Vol. 102, Issue 5, pp. 1016-23, 1998

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (Middle Region) antibody (ABIN453773) Western blot analysis of NR1I2 Antibody (Center) in HL-60 cell line lysates (35ug/lan...