anti-Human Nuclear Receptor Subfamily 1, Group H, Member 3 Antikörper für Enzyme Immunoassay

Recommended Nuclear Receptor Subfamily 1, Group H, Member 3 Antibody

Antigen
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antikörper
  • NR1H3
  • LXR-a
  • LXRA
  • RLD-1
  • AU018371
  • LXR
  • RLD1
  • Unr1
  • LXRalpha
  • LXR-alpha
  • im:7141239
  • wu:fd59b01
  • zgc:113339
  • zgc:158542
  • nuclear receptor subfamily 1 group H member 3
  • nuclear receptor subfamily 1, group H, member 3
  • NR1H3
  • nr1h3
  • Nr1h3
Epitop
N-Term
15
12
10
9
8
8
7
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
133
70
65
11
9
9
7
6
6
5
4
4
3
2
2
2
2
2
2
Wirt
Kaninchen
122
15
6
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
5
5
2
2
2
2
2
2
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
119
58
26
15
9
8
7
6
4
2
2
2
1
1
Optionen

Bilder

Produktnummer ABIN615720
$ 495.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Clonality References Details
1 ABIN5556294 EIA FACS WB Rabbit Ig Fraction AA 232-262, Middle Region Polyclonal 0
1 ABIN5554977 EIA IHC (p) WB Rabbit IgG N-Term Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antikörper
Epitop N-Term
(15), (12), (10), (9), (8), (8), (7), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(133), (70), (65), (11), (9), (9), (7), (6), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2)
Wirt Kaninchen
(122), (15), (6)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(7), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(119), (58), (26), (15), (9), (8), (7), (6), (4), (2), (2), (2), (1), (1)
Hersteller

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität This antibody reacts to the N-term of Liver X Receptor Alpha (LXR Alpha/NR1H3).
Reinigung Immunoaffinity Chromatography
Immunogen NR1H3 antibody was raised against synthetic peptide - KLH conjugated Genename: NR1H3

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung NR1H3 (NR1H3 Antibody Abstract)
Hintergrund Liver X receptor alpha (LXR alpha), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect the transport and catabolism of cholesterol as well as fatty acid metabolism. LXR alpha also appears to be an important insulin mediating factor in the regulation of lipogenesis. LXR alpha is known to be activated by oxysterols and to regulate a wide range of genes, including members of the ATP-binding cassette (ABC) superfamily of transporter proteins (ABCA1 and ABCG1), surface constituents of plasma lipoproteins like apolipoprotein E, and cholesterol ester transport protein. The induced expression of LXR alpha may be related to foam-cell formation in atherosclerotic lesions. As a result, LXR alpha has been suggested as a potential therapeutic target for treating atherosclerosis. LXR alpha forms a heterodimer with RXR alpha and binds the DR4-type cis-element. Recently LXR alpha has been shown to act as a cAMP-responsive nuclear modulator of renin and c-myc expression, suggesting a possible involvement of LXR alpha in the cardiovascular system and in general gene transcription.Synonyms: LXRA, Liver X receptor alpha, Nuclear orphan receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR-alpha
Gen-ID 10062
NCBI Accession NP_001123573
UniProt Q13133
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Konzentration 1,0 mg/mL
Buffer PBS containing 0.02 % sodium azide as preservative
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibody (ABIN615720) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibody (ABIN615720) Western blot analysis of LXR-A in rat liver tissue lysate with LXR-A antibody at (A) ...