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anti-Human Androgen Receptor Antikörper:
anti-Mouse (Murine) Androgen Receptor Antikörper:
anti-Rat (Rattus) Androgen Receptor Antikörper:
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Human Monoclonal Androgen Receptor Primary Antibody für IHC (p), IHC - ABIN252555
Lin, Hu, Yang, Altuwaijri, Chen, Kang, Chang: Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. in The Journal of biological chemistry 2003
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Human Monoclonal Androgen Receptor Primary Antibody für IHC (fro), IP - ABIN967444
Chang, Wang, DeLuca, Ross, Shih: Characterization of human androgen receptor overexpressed in the baculovirus system. in Proceedings of the National Academy of Sciences of the United States of America 1992
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Human Monoclonal Androgen Receptor Primary Antibody für IHC, ELISA - ABIN1724724
Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells. in Cancer research 2007
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Human Polyclonal Androgen Receptor Primary Antibody für ICC, IHC (p) - ABIN3044419
Xiang-Yun, Ying-Wen, Chen-Jing, Jiu-Jiu, Qi, Bo, Zu-Yue: Possible mechanism of benign prostatic hyperplasia induced by androgen-estrogen ratios in castrated rats. in Indian journal of pharmacology 2011
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Human Monoclonal Androgen Receptor Primary Antibody für ELISA, WB - ABIN968966
Lindström, Wiklund, Adami, Bälter, Adolfsson, Grönberg: Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development. in Cancer research 2006
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Human Monoclonal Androgen Receptor Primary Antibody für ELISA, WB - ABIN965588
Zong, Chi, Wang, Yang, Zhang, Chen, Jiang, Li, Hong, Wang, Yun, Gu: Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor. in Molecular and cellular biology 2007
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Human Monoclonal Androgen Receptor Primary Antibody für IHC (f), IHC (fro) - ABIN2688843
Fuller: The steroid receptor superfamily: mechanisms of diversity. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992
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Human Polyclonal Androgen Receptor Primary Antibody für ChIP, ELISA - ABIN250260
Trapman, Klaassen, Kuiper, van der Korput, Faber, van Rooij, Geurts van Kessel, Voorhorst, Mulder, Brinkmann: Cloning, structure and expression of a cDNA encoding the human androgen receptor. in Biochemical and biophysical research communications 1988
Human Polyclonal Androgen Receptor Primary Antibody für IF (p), IHC (p) - ABIN725240
Madka, Mohammed, Li, Zhang, Biddick, Patlolla, Lightfoot, Towner, Wu, Steele, Kopelovich, Rao: Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo. in Cancer prevention research (Philadelphia, Pa.) 2016
Human Monoclonal Androgen Receptor Primary Antibody für CyTOF, FACS - ABIN4900460
Rode, Boehm: Regenerative capacity of adult cortical thymic epithelial cells. in Proceedings of the National Academy of Sciences of the United States of America 2012
Data show that androgen receptor (AR) status was significantly associated with brain metastasis in epithelial ovarian cancer (EOC).
Wild-type and mutant AR physically interact with the APC (zeige APC Antikörper)/CCdh1 complex in a ligand-dependent fashion without being targeted for proteasomal degradation.
HER2 (zeige ERBB2 Antikörper)(+) and triple-negative breast cancer cell lines were treated with AR antagonist plus anti-HER2 (zeige ERBB2 Antikörper) mAb trastuzumab or mTOR (zeige FRAP1 Antikörper) inhibitor everolimus..AR antagonists synergize with FDA-approved breast cancer therapies such as everolimus and trastuzumab through distinct mechanisms. Treatment combinations are effective in trastuzumab-resistant HER2 (zeige ERBB2 Antikörper)(+) breast cancer cells in vivo
Data indicate that androgen receptor serine515 (AR-515) is a potential prognostic marker and therapeutic target for triple negative breast cancer (TNBC).
men carrying shorter (<22) AR CAG repeats have lower HDL (zeige HSD11B1 Antikörper)-C level and increased risk of hypertension. The androgenic activity may differ due to the polymorphic length of CAG repeats of the AR gene.
Inhibition of endogenous miR (zeige MLXIP Antikörper)-30b-3p and miR (zeige MLXIP Antikörper)-30d-5p enhanced AR expression and androgen-independent cell growth.
Study highlights how androgen receptor itself functions is an important step in elucidating the molecular basis for androgen-independent prostate tumors.Translocation of AR to improper gene promoter elements or DNA-binding sites can result in an alteration in gene expression and thus normal prostate function. AR regulation of mir (zeige MLXIP Antikörper)-206 is an important mechanism for prostate tumor progression. [review]
The progesterone receptor (zeige PGR Antikörper) B (PRB (zeige RB1 Antikörper)) and androgen Receptor (AR) mRNA levels were highest in tumors.
Findings provide the first evidence for a link between the androgen receptor gene and moral judgment and highlight the role of androgens in moral foundations.
the deregulation of androgen receptor (AR) expression is a driver of chromatin relaxation and that AR/androgen-regulated bromodomain-containing proteins (BRDs) mediate this effect.
androgen receptor has a central role in the spontaneous regeneration of myelin
Data (including data from studies using transgenic/knockout mice) suggest that AR in insulin (zeige INS Antikörper)-secreting cells is involved in insulin (zeige INS Antikörper) secretion and inflammation; AR-deficient insulin (zeige INS Antikörper)-secreting cells exhibit altered expression of genes involved in inflammation and insulin (zeige INS Antikörper) secretion demonstrating importance of androgen action in functions of insulin (zeige INS Antikörper)-secreting cells.
Cyclic mechanical stretch modulated the proliferation of C2C12 cells, which may be attributed to the alterations of AR via IGF-1 (zeige IGF1 Antikörper)-PI3K/Akt (zeige AKT1 Antikörper) and IGF-1 (zeige IGF1 Antikörper)-MAPK (p38 (zeige MAPK1 Antikörper), ERK1/2) pathways in C2C12 cells.
We show AR expressed in cancer-associated fibroblasts (CAFs) contributes to the tumor-promoting abilities that CAFs exert on epithelial prostate cancer cells. Further, we found that decreased AR expression in CAFs is also associated with an increase in stem cell marker gene expression in prostate cancer epithelial cells.
in clear cell renal cell carcinoma (zeige MOK Antikörper), enhances lung and liver metastases, while suppressing lymphatic metastasis
Glandular epithelial AR inactivation (with persistent stromal AR action) enhanced PTEN deletion-induced uterine pathology possibly by downregulating progesterone receptor (zeige PGR Antikörper) expression in the uterus.
CDK2 (zeige CDK2 Antikörper) phosphorylates polyQ-AR specifically at Ser (zeige SIGLEC1 Antikörper)(96). Phosphorylation of polyQ-AR by CDK2 (zeige CDK2 Antikörper) increased protein stabilization and toxicity and is negatively regulated by the adenylyl cyclase/protein kinase A signaling pathway in spinobulbar muscular atrophy.
experimental manipulation of the prenatal androgen level, by blocking the androgen receptor with flutamide or activating the androgen receptor with dihydrotestosterone (DHT), leads to changes in the length of the fingers of all paws in males and females.
Silencing of androgen receptor rescues the muscular spinal atrophy transgenic mice.
Taken together, our findings provide evidence for a novel crosstalk and a crossregulation between ING1 and ING2 in regulating androgen receptor-mediated transactivation and suggest that ING2 acts as a novel corepressor that inhibits AR signaling, prostate cancer cell growth, and migration.
substantial up-regulation of androgen receptor expression during trophoblast giant cell differentiation suggests that androgens may be related to this process and are active products of bovine placental steroidogenesis
no association between the AR CAG polymorphism and the relative risk of prostate cancer in white Brazilian individuals with a CAG repeat (zeige CELF3 Antikörper)
FSHR (zeige FSHR Antikörper) is specifically regulated through androgen receptor in granulosa cells
Roles of IGF-I (zeige IGF1 Antikörper) and the estrogen, androgen and IGF-I (zeige IGF1 Antikörper) receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.
In GD20 and PD2 (zeige PAF1 Antikörper) males we found the reduction of the luminal compartment, inflammatory changes, decreased androgen receptor and increased Cx43 (zeige GJA1 Antikörper) expression
Data suggest that signal transduction involving androgen receptor is involved in apoptosis of granulosa cells (as seen in follicular atresia).
Pig ejaculated spermatozoa express androgen receptor.
Androgen receptor (AR) and Wilms' tumor gene 1 expression dramatically decreased after heat treatment in Sertoli cells
Sertoli cell maturation during puberty in the stallion was accompanied by a reduced expression of anti-Mullerian hormone (zeige AMH Antikörper) and its receptor, arrest of cell proliferation, increased expression of androgen receptor
The vesicular gland of castrated goats showed significantly lower AR and COX-2 (zeige COX2 Antikörper) immuno-expression than intact goats indicating that both AR and COX-2 (zeige COX2 Antikörper) are androgen dependent.
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
androgen nuclear receptor variant 2
, dihydrotestosterone receptor
, nuclear receptor subfamily 3 group C member 4
, testicular feminization
, androgen receptor (Testicular feminization), same as Tfm
, androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
, androgen receptor AR
, Ar beta
, androgen receptor
, prostate androgen receptor