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Human Monoclonal Androgen Receptor Primary Antibody für IHC (p), IHC - ABIN252555
Lin, Hu, Yang, Altuwaijri, Chen, Kang, Chang: Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. in The Journal of biological chemistry 2003
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Human Monoclonal Androgen Receptor Primary Antibody für IHC, ELISA - ABIN1724724
Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells. in Cancer research 2007
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Human Polyclonal Androgen Receptor Primary Antibody für ICC, IHC (p) - ABIN3044419
Xiang-Yun, Ying-Wen, Chen-Jing, Jiu-Jiu, Qi, Bo, Zu-Yue: Possible mechanism of benign prostatic hyperplasia induced by androgen-estrogen ratios in castrated rats. in Indian journal of pharmacology 2011
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Human Monoclonal Androgen Receptor Primary Antibody für ELISA, WB - ABIN968966
Lindström, Wiklund, Adami, Bälter, Adolfsson, Grönberg: Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development. in Cancer research 2006
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Human Monoclonal Androgen Receptor Primary Antibody für ELISA, WB - ABIN965588
Zong, Chi, Wang, Yang, Zhang, Chen, Jiang, Li, Hong, Wang, Yun, Gu: Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor. in Molecular and cellular biology 2007
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Human Monoclonal Androgen Receptor Primary Antibody für IHC (f), IHC (fro) - ABIN2688843
Fuller: The steroid receptor superfamily: mechanisms of diversity. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992
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Human Polyclonal Androgen Receptor Primary Antibody für ChIP, ELISA - ABIN250260
Trapman, Klaassen, Kuiper, van der Korput, Faber, van Rooij, Geurts van Kessel, Voorhorst, Mulder, Brinkmann: Cloning, structure and expression of a cDNA encoding the human androgen receptor. in Biochemical and biophysical research communications 1988
Human Polyclonal Androgen Receptor Primary Antibody für IF (p), IHC (p) - ABIN725240
Madka, Mohammed, Li, Zhang, Biddick, Patlolla, Lightfoot, Towner, Wu, Steele, Kopelovich, Rao: Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo. in Cancer prevention research (Philadelphia, Pa.) 2016
Human Monoclonal Androgen Receptor Primary Antibody für CyTOF, FACS - ABIN4900460
Rode, Boehm: Regenerative capacity of adult cortical thymic epithelial cells. in Proceedings of the National Academy of Sciences of the United States of America 2012
Targeting the Malat1/AR-v7 axis via Malat1-siRNA or ASC (zeige PYCARD Antikörper)-J9 can be developed as a new therapy to better suppress enzalutamide-resistant prostate cancer progression.
Results identified the N-terminal region of AR-V7 (splice variants) that interacts with the diffuse B-cell lymphoma homology (DH) domain of Vav3 (zeige VAV3 Antikörper) which increases its expression in castration-resistant prostate cancer (CRPC).
The single nucleotide polymorphism G1733A of the androgen receptor gene is significantly associated with recurrent spontaneous abortions in Mexican patients.
Report increased androgen receptor gene copy number and protein expression in treatment-naive prostate cancer.
Here the authors show that the AF-1 (zeige EFNA5 Antikörper) domain of AR is bound by the cochaperone Bag-1L.
Mechanistically, AR modulated cytokine CXCL5 (zeige CXCL5 Antikörper) expression by altering AKT (zeige AKT1 Antikörper) --> NF-kappaB (zeige NFKB1 Antikörper) signaling, and interruption of AKT (zeige AKT1 Antikörper) --> NF-kappaB (zeige NFKB1 Antikörper) --> CXCL5 (zeige CXCL5 Antikörper) signaling using either specific inhibitors or siRNA suppressed AR-enhanced EC recruitment and AR-EC-promoted RCC (zeige XRCC1 Antikörper) progression.
Data show that androgen receptor variant AR-V9 (AR-V9) may play a significant role in promoting androgen-independent growth of castration-resistant prostate cancer (CRPC) cells, and that AR-V9 mRNA expression in CRPC metastases was predictive of primary resistance to abiraterone acetate.
Alterations in the androgen receptor are associated with endocrine treatment outcomes in castration-resistance prostate cancer.
there is association between the AR CAG repeat (zeige CELF3 Antikörper) polymorphism and ovarian cancer risk (Meta-Analysis).
Prostate cancer cells expressing an S273A mutant of CHIP have attenuated AR degradation upon 2-ME treatment compared with cells expressing wild-type CHIP, supporting the idea that CHIP phosphorylation by Aurora A (zeige AURKA Antikörper) activates its E3 ligase activity for the AR
Results provide evidence that androgen receptor is expressed from prenatal stages in mouse heart, supporting the proposition that androgens could be involved in mammalian heart development.
The role of ERbeta (zeige ESR2 Antikörper) in opposing AR signaling, proliferation, and inflammation suggests that ERbeta (zeige ESR2 Antikörper)-selective agonists may be used to prevent progression of prostate cancer, prevent fibrosis and development of benign prostatic hyperplasia, and treat prostatitis.
androgen receptor has a central role in the spontaneous regeneration of myelin
Data (including data from studies using transgenic/knockout mice) suggest that AR in insulin (zeige INS Antikörper)-secreting cells is involved in insulin (zeige INS Antikörper) secretion and inflammation; AR-deficient insulin (zeige INS Antikörper)-secreting cells exhibit altered expression of genes involved in inflammation and insulin (zeige INS Antikörper) secretion demonstrating importance of androgen action in functions of insulin (zeige INS Antikörper)-secreting cells.
Cyclic mechanical stretch modulated the proliferation of C2C12 cells, which may be attributed to the alterations of AR via IGF-1 (zeige IGF1 Antikörper)-PI3K/Akt (zeige AKT1 Antikörper) and IGF-1 (zeige IGF1 Antikörper)-MAPK (p38 (zeige MAPK1 Antikörper), ERK1/2) pathways in C2C12 cells.
We show AR expressed in cancer-associated fibroblasts (CAFs) contributes to the tumor-promoting abilities that CAFs exert on epithelial prostate cancer cells. Further, we found that decreased AR expression in CAFs is also associated with an increase in stem cell marker gene expression in prostate cancer epithelial cells.
in clear cell renal cell carcinoma (zeige MOK Antikörper), enhances lung and liver metastases, while suppressing lymphatic metastasis
Glandular epithelial AR inactivation (with persistent stromal AR action) enhanced PTEN deletion-induced uterine pathology possibly by downregulating progesterone receptor (zeige PGR Antikörper) expression in the uterus.
CDK2 (zeige CDK2 Antikörper) phosphorylates polyQ-AR specifically at Ser (zeige SIGLEC1 Antikörper)(96). Phosphorylation of polyQ-AR by CDK2 (zeige CDK2 Antikörper) increased protein stabilization and toxicity and is negatively regulated by the adenylyl cyclase/protein kinase A signaling pathway in spinobulbar muscular atrophy.
experimental manipulation of the prenatal androgen level, by blocking the androgen receptor with flutamide or activating the androgen receptor with dihydrotestosterone (DHT), leads to changes in the length of the fingers of all paws in males and females.
substantial up-regulation of androgen receptor expression during trophoblast giant cell differentiation suggests that androgens may be related to this process and are active products of bovine placental steroidogenesis
no association between the AR CAG polymorphism and the relative risk of prostate cancer in white Brazilian individuals with a CAG repeat (zeige CELF3 Antikörper)
FSHR (zeige FSHR Antikörper) is specifically regulated through androgen receptor in granulosa cells
Roles of IGF-I (zeige IGF1 Antikörper) and the estrogen, androgen and IGF-I (zeige IGF1 Antikörper) receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.
In GD20 and PD2 (zeige PAF1 Antikörper) males we found the reduction of the luminal compartment, inflammatory changes, decreased androgen receptor and increased Cx43 (zeige GJA1 Antikörper) expression
Data suggest that signal transduction involving androgen receptor is involved in apoptosis of granulosa cells (as seen in follicular atresia).
Pig ejaculated spermatozoa express androgen receptor.
Androgen receptor (AR) and Wilms' tumor gene 1 expression dramatically decreased after heat treatment in Sertoli cells
Zebrafish males lacking the androgen receptor courted females significantly less, showing reduced levels of stereotypic behaviors. Consistent with previous studies, disrupting androgen mechanisms can lead to behavioral changes with potential fitness consequences.
Sertoli cell maturation during puberty in the stallion was accompanied by a reduced expression of anti-Mullerian hormone (zeige AMH Antikörper) and its receptor, arrest of cell proliferation, increased expression of androgen receptor
The vesicular gland of castrated goats showed significantly lower AR and COX-2 (zeige COX2 Antikörper) immuno-expression than intact goats indicating that both AR and COX-2 (zeige COX2 Antikörper) are androgen dependent.
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
androgen nuclear receptor variant 2
, dihydrotestosterone receptor
, nuclear receptor subfamily 3 group C member 4
, testicular feminization
, androgen receptor (Testicular feminization), same as Tfm
, androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)
, androgen receptor AR
, Ar beta
, androgen receptor
, prostate androgen receptor