anti-Human KHDRBS1 Antikörper für Flow Cytometry

Recommended KHDRBS1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) Antikörper
  • Sam68
  • p62
  • p68
  • fj90g10
  • khdrbs1
  • wu:fa18g12
  • wu:fa56c01
  • wu:fc91b01
  • wu:fj90g10
  • zgc:113899
  • KHDRBS1
  • P62
  • KH RNA binding domain containing, signal transduction associated 1
  • KH domain containing, RNA binding, signal transduction associated 1a
  • KH domain containing, RNA binding, signal transduction associated 1
  • KH domain containing, RNA binding, signal transduction associated 1 S homeolog
  • KHDRBS1
  • khdrbs1a
  • khdrbs1
  • Khdrbs1
  • khdrbs1.S
Reaktivität
Human
106
69
39
10
9
8
7
5
4
2
1
1
1
Wirt
Kaninchen
116
9
4
1
Klonalität
Polyklonal
Konjugat
Dieser KHDRBS1 Antikörper ist unkonjugiert
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
111
37
34
23
19
15
13
6
4
3
3
2
1
Hersteller
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Bilder

Produktnummer ABIN2666108
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5698031 ELISA FACS IF IHC IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN5870143 ELISA FACS IF/ICC IHC IP WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN2666107 FACS Rabbit Anmelden zum Anzeigen Polyclonal 0

General

Antigen KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) Antikörper
Reaktivität Human
(106), (69), (39), (10), (9), (8), (7), (5), (4), (2), (1), (1), (1)
Wirt Kaninchen
(116), (9), (4), (1)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser KHDRBS1 Antikörper ist unkonjugiert
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS)
(111), (37), (34), (23), (19), (15), (13), (6), (4), (3), (3), (2), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-KHDRBS1 Antikörper

Target Details KHDRBS1 Anwendungsinformationen Handhabung Referenzen für anti-KHDRBS1 Antikörper (ABIN2666108) Bilder
Reinigung The antibody was purified by affinity chromatography.
Klon Poly6477
Plasmids, Primers & others

Target Details KHDRBS1

Produktdetails anti-KHDRBS1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-KHDRBS1 Antikörper (ABIN2666108) Bilder zurück nach oben
Antigen
Andere Bezeichnung P62 (KHDRBS1 Antibody Abstract)
Hintergrund The p62 protein, also called sequestosome 1 (SQSTM1), is a ubiquitin-binding scaffold protein that colocalizes with ubiquitinated protein aggregates in many neurodegenerative diseases and proteinopathies of the liver. The protein is able to polymerize via an N-terminal PB1 domain and can interact with ubiquitinated proteins via the C-terminal UBA domain. Also, p62/SQSTM1 binds directly to LC3 and GABARAP family proteins via a specific sequence motif. The protein is itself degraded by autophagy and may serve to link ubiquitinated proteins to the autophagic machinery to enable their degradation in the lysosome. Recent studies have revealed a novel function for p62 in innate immunity.
Pathways NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie

Anwendungsinformationen

Produktdetails anti-KHDRBS1 Antikörper Target Details KHDRBS1 Handhabung Referenzen für anti-KHDRBS1 Antikörper (ABIN2666108) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-KHDRBS1 Antikörper Target Details KHDRBS1 Anwendungsinformationen Referenzen für anti-KHDRBS1 Antikörper (ABIN2666108) Bilder zurück nach oben
Format Liquid
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Upon receipt, store frozen at -20°C.

Referenzen für anti-KHDRBS1 Antikörper (ABIN2666108)

Produktdetails anti-KHDRBS1 Antikörper Target Details KHDRBS1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Diessner, Bruttel, Stein, Horn, Häusler, Dietl, Hönig, Wischhusen: "Targeting of preexisting and induced breast cancer stem cells with trastuzumab and trastuzumab emtansine (T-DM1)." in: Cell death & disease, Vol. 5, pp. e1149, 2014

Zheng, Shahnazari, Brech, Lamark, Johansen, Brumell: "The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 9, pp. 5909-16, 2009

Pankiv, Clausen, Lamark, Brech, Bruun, Outzen, a: "p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy." in: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24131-45, 2007

Falchetti, Di Stefano, Marini, Del Monte, Gozzini, Masi, Tanini, Amedei, Carossino, Isaia, Brandi: "Segregation of a M404V mutation of the p62/sequestosome 1 (p62/SQSTM1) gene with polyostotic Paget's disease of bone in an Italian family." in: Arthritis research & therapy, Vol. 7, Issue 6, pp. R1289-95, 2005

Bjørkøy, Lamark, Brech, Outzen, Perander, Overvatn, Stenmark, Johansen: "p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death." in: The Journal of cell biology, Vol. 171, Issue 4, pp. 603-14, 2005

Bilder

Produktdetails anti-KHDRBS1 Antikörper Target Details KHDRBS1 Anwendungsinformationen Handhabung Referenzen für anti-KHDRBS1 Antikörper (ABIN2666108) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) antibody (ABIN2666108) anti-KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1) antibody