anti-PKC iota (PRKCI) Antikörper

Human Protein Kinase C, iota (PRKCI) Interaktionspartner

1. 14-3-3zeta (zeige YWHAZ Antikörper) and aPKC-iota synergistically facilitate EMT (zeige ITK Antikörper) of CCA (zeige FBN2 Antikörper) via GSK-3beta/Snail (zeige SNAI1 Antikörper) signalling pathway.

2. In human ovarian cancers, high PRKCI expression correlates with high expression (zeige TNF Antikörper) of TNFalpha and YAP1 and low infiltration of cytotoxic T cells

3. promotes epithelial-mesenchymal transition and induces immunosuppression through the aPKC-iota/P-Sp1 (zeige PSG1 Antikörper)/Snail (zeige SNAI1 Antikörper) signaling pathway in cholangiocarcinoma

4. Polarity signaling via CDC42 (zeige CDC42 Antikörper)/atypical protein kinase C (zeige PRKCZ Antikörper) can affect the dynamic turnover of the intermediate filament network to promote the polarization of the network itself.

5. a PI3K (zeige PIK3CA Antikörper)/PKCiota/cyclin E (zeige CCNE1 Antikörper) signaling pathway as a therapeutic target during ovarian tumorigenesis

6. results identify a novel role of PHLPP (zeige PHLPP1 Antikörper) in regulating aPKC and cell polarity.

7. the polarity function of PRKCI during cavitation

8. 14-3-3zeta (zeige YWHAZ Antikörper)-mediated invasion of cancer cells was found to upregulate Snail (zeige SNAI1 Antikörper) through the activation of atypical protein kinase C (zeige PRKCZ Antikörper) (aPKC).

9. Upregulated expression of PRKCI and interaction with CDK7 (zeige CDK7 Antikörper) is associated with esophageal squamous cell carcinoma.

10. the results revealed that PRKCI rs546950 variant decreased the risk of prostate cancer in an Iranian population

Zebrafish Protein Kinase C, iota (PRKCI) Interaktionspartner

1. Zebrafish pronephros tubulogenesis and epithelial identity maintenance are reliant on the polarity proteins Prkc iota and zeta.

2. a loss of zBves affects the proteins involved in the pathway of the PAR (zeige AFG3L2 Antikörper) junctional complex, especially aPKC, and both aPKC and Bves (zeige BVES Antikörper) are indispensable to claudin expression.

3. Heart and soul/PRKCi and nagie oko/Mpp5 (zeige MPP5 Antikörper) regulate myocardial coherence and remodeling during cardiac morphogenesis (zeige XIRP1 Antikörper).

4. PrkCi function and planar divisions are necessary for asymmetric, self-renewing division of spinal cord precursors.

Mouse (Murine) Protein Kinase C, iota (PRKCI) Interaktionspartner

1. This study demonstrated hat (zeige HAT Antikörper) under physiological conditions, PKCiota/lambda is essential for hippocampal early-LTP (zeige SCP2 Antikörper) and long-term memory.

2. the aPKC-CBP (zeige CREBBP Antikörper) pathway is a homeostatic compensatory mechanism that modulates hippocampal neurogenesis and memory in an age-dependent manner in response to reduced CREB (zeige CREB1 Antikörper) activity.

3. he oncogenic activity of PRKCI relates in part to the up-regulation of TNFalpha (zeige TNF Antikörper) to promote an immune-suppressive tumor microenvironment characterized by an abundance of myeloid-derived suppressor cells and inhibition of cytotoxic T-cell infiltration

4. Selective deletion of the aPKC isoform Pkc (zeige PKC Antikörper)-lambda in proopiomelanocortin (POMC (zeige POMC Antikörper)) neurons disrupts leptin (zeige LEP Antikörper) action, reduces melanocortin content in the paraventricular nucleus, and markedly increases susceptibility to obesity, glucose intolerance, and insulin (zeige INS Antikörper) resistance specifically in HFD-fed male mice.

5. results identify a novel role of PHLPP (zeige PHLPP1 Antikörper) in regulating aPKC and cell polarity.

6. Prkci and its downstream partners direct polarized cell division of luminal myocardial cells to drive trabeculation in the nascent heart.

7. Prkci regulates expansion of various stem cells via Notch (zeige NOTCH1 Antikörper)-dependent pathway.

8. PKClambda/iota could be a crucial regulator of mitochondrial function and energy metabolism in stem cells and other cellular contexts

9. Asymmetric division and CD8+ T lymphocyte fate specification is regulated by protein kinase Czeta and protein kinase Clambda.

10. adenoviral-mediated supplementation of hepatic PKC-lambda induced a diabetic state in heterozygous PKC-lambda knockout mice.

Cow (Bovine) Protein Kinase C, iota (PRKCI) Interaktionspartner

1. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.