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AKAP13 Antigen Profile

Beschreibung des Gens

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta.

Alternative names and synonyms associated with AKAP13

  • A-kinase anchoring protein 13 (AKAP13) ELISA Kit
  • A-kinase anchoring protein 13 S homeolog (akap13.S) ELISA Kit
  • A kinase (PRKA) anchor protein 13 (akap13) ELISA Kit
  • A-kinase anchoring protein 13 (Akap13) ELISA Kit
  • A kinase (PRKA) anchor protein 13 (Akap13) ELISA Kit
  • AKAP13 ELISA Kit
  • brx ELISA Kit
  • lbc ELISA Kit
  • ha-3 ELISA Kit
  • ht31 ELISA Kit
  • c-lbc ELISA Kit
  • MGC81410 ELISA Kit
  • akap-lbc ELISA Kit
  • arhgef13 ELISA Kit
  • proto-lb ELISA Kit
  • proto-lbc ELISA Kit
  • AKAP-13 ELISA Kit
  • AKAP-Lbc ELISA Kit
  • HA-3 ELISA Kit
  • Ht31 ELISA Kit
  • PRKA13 ELISA Kit
  • p47 ELISA Kit
  • 1700026G02Rik ELISA Kit
  • 5730522G15Rik ELISA Kit
  • 5830460E08Rik ELISA Kit

Bezeichner auf Proteinebene für AKAP13

A kinase (PRKA) anchor protein 13 , A kinase anchor protein 13 isoform-like , A-kinase anchor protein 13-like , A-kinase anchor protein 13 , a-kinase anchor protein 13-like , A-kinase anchoring protein , LBC oncogene , breast cancer nuclear receptor-binding auxiliary protein , guanine nucleotide exchange factor Lbc , human thyroid-anchoring protein 31 , lymphoid blast crisis oncogene , non-oncogenic Rho GTPase-specific GTP exchange factor , protein kinase A-anchoring protein 13 , protein kinase A anchoring protein Rt31 , type II cAMP-dependent protein kinase anchoring protein Ht31

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