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Dog (Canine) Monoclonal Adenosine A2a Receptor Primary Antibody für CyTOF, FACS - ABIN447986
Khoa, Montesinos, Reiss, Delano, Awadallah, Cronstein: Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Dog (Canine) Polyclonal Adenosine A2a Receptor Primary Antibody für ICC, IF - ABIN152752
Ren, Lin, Cao, Yang, Lu, Liu, Chen, Yang, Tian, Wang, Li, Wang, Chen, Ji, Zhang: CD73 is associated with poor prognosis in HNSCC. in Oncotarget 2016
Rhesus Monkey Polyclonal Adenosine A2a Receptor Primary Antibody für ELISA, WB - ABIN185549
Rétey, Adam, Honegger, Khatami, Luhmann, Jung, Berger, Landolt: A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans. in Proceedings of the National Academy of Sciences of the United States of America 2005
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Human Polyclonal Adenosine A2a Receptor Primary Antibody für IF (p), IHC (p) - ABIN686797
Cao, Dai, Wei, Han, Guan, Li, Liu, Xiao, Li: Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus. in Physiology & behavior 2017
The presence of two different isoforms in the myocardium close to the insertion of pacing is suggestive of a differential state-specific expression of A2AR in cardiac tissue.
Ex vivo lung perfusion with adenosine A2A receptor agonist allows prolonged cold preservation of lungs donated after cardiac death.
Adenosine A2A receptor contributes to ischemic brain damage in newborn piglet.
Pretreatment strategy with adenosine A2A receptor agonist attenuates reperfusion injury in a preclinical porcine lung transplantation model.
Activation of adenosine A(2A) receptors inhibited ROS (zeige ROS1 Antikörper) production by LPS (zeige IRF6 Antikörper)-stimulated equine neutrophils in a cAMP-dependent manner.
Adenosine A2A receptor immunoreactivity is localized at the highest levels of the striatum and external globus pallidus.
These data indicate that low [Na(+)] is required to allow large agonist-induced structural changes in A2AR, and that patterns of sidechain dynamics substantially differ between agonist (NECA) and inverse agonist (ZM241385) bound receptors, with the inverse agonist suppressing fast picosecond-nanosecond timescale motions at the G protein binding site.
Low adenosine A2a receptor expression is associated with ulcerative colitis.
Results demonstrate that A2AR act on GR nuclear translocation and GR-dependent transcriptional regulation which suggest that A2AR is a major regulator of GR function and that this functional interconnection may be a trigger to age-related memory deficits.
the present study indicates that A2bR (zeige ADORA2B Antikörper) may play a potential oncogenic role in BUC progression and act as a potential biomarker to identify BUC patients with poor clinical outcomes.
Report prognostic impact of ADORA2A expression in non-small lung cancers.
genetic association studies in population in Germany: Data suggest that an SNP in ADORA2A (1976T/C, rs5751876) is associated with interoceptive (resting) and exteroceptive (executive function/task-based) processing in frontal lobe and insular cortex neural networks. Facilitated processing of interoceptive/exteroceptive information in salience network is suggested to promote development of anxiety and anxiety disorders.
A2A receptor stimulation promotes collagen type III synthesis via the activation of canonical and non-canonical beta-catenin (zeige CTNNB1 Antikörper), consistent with a role for A2A receptors in dermal fibrosis and scarring.
It is significantly associated with hippocampal volume and the minor allele of rs9608282 in ADORA2A is associated with larger hippocampal volumes and better memory.
Study corroborated results from a previous report that described interactions between ADORA2A and CYP1A2 (zeige CYP1A2 Antikörper) polymorphisms and coffee consumption in Parkinson's disease.
However, the contribution of the A2AR to the control of impulsive reward seeking remains unknown. Using mice that were exposed to differential reward of low rate (DRL) schedules during Pavlovian-conditioning, second-order schedule discrimination, and the 5-choice serial reaction time task (5 (zeige KCNK15 Antikörper)-CSRTT), we demonstrate that deficits of A2AR function promote impulsive responses.
Body weight was significantly smaller in A2AR-KO mice at the age of 6 months
A2AR activation enhances its interaction with endothelial glutamate (zeige GRIN1 Antikörper) transporters. Inhibition of A2AR rescued dysfunction of brain endothelial glutamate (zeige GRIN1 Antikörper) transporters.
The astrocytic Lrp4 (zeige CORIN Antikörper) plays an important role in ischemic brain injury response. Lrp4 (zeige CORIN Antikörper) deficiency in astrocytes seems to be protective in response to ischemic brain injury, likely because of the increased ATP release and adenosine-A2AR signaling.
the potential effects of the A2A adenosine receptor (A2AR) antagonist SCH (zeige NF2 Antikörper) 5826 (SCH (zeige NF2 Antikörper)) and agonist CGS 21680 (CGS) on behavior (self-grooming), hot plate test results, and expression levels of IL-17A (zeige IL17A Antikörper)(+), RORgammat(+), Foxp3 (zeige FOXP3 Antikörper)(+), and IL-10 (zeige IL10 Antikörper)(+) in CD4 (zeige CD4 Antikörper)(+) T spleen cells in BTBR and C57BL/6 (B6) mice, were investigated.
Absence of A2AAR increases cochlear resistance to acoustic trauma.
Behavioral, anatomical and neurochemical studies to assess psychotic-like symptoms in adult male and female A2AR KO and wild-type littermates. Results bolster the adenosine hypothesis of schizophrenia by demonstrating behavioral and anatomical alterations associated with the specific deletion of adenosine A2AR. These findings resemble most of the relevant phenotype features of the human disorder.
Adenosine receptor A2A drives pathological angiogenesis in the oxygen-induced retinopathy mouse model by promoting glycolysis in endothelial cells via the ERK (zeige EPHB2 Antikörper)/Akt (zeige AKT1 Antikörper)/HIF-1alpha (zeige HIF1A Antikörper) pathway.
it is concluded that the anxiolytic-like activities of rubimetide and typical agonist peptides of the FPR2 were mediated successively by the PGD2-DP1 receptor, adenosine-A2A receptor, and GABA-GABAA receptor systems downstream of the FPR2.
Study focused on the impact of A2A receptor deletion (A2A receptor knockout, A2AKO) on motivation for social exploration. Although A2AKO mice showed an anxious profile, they displayed higher levels of sociability and were less sensitive to social novelty. c-Fos immunoreactivity in A2AKO mice was higher in anterior cingulate and amygdala compared to wild type mice.
Data indicate A2ARs exert minor effects in un-stressed myocardium and selectively suppress NFkappaB and JAK (zeige JAK3 Antikörper)-STAT (zeige STAT1 Antikörper) signalling and cardiac injury without influencing cardiac depression in endotoxemia.
Study reveals presence of adenosine A(2A) and A(2B (zeige ADRA2B Antikörper)) receptors as well as a role for them in lacrimal gland secretion, and especially in synergy with purinergic and cholinergic stimulation.
This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
adenosine A2a receptor
, adenosine receptor A2a
, adenosine receptor A2a.1
, adenosine receptor subtype A2a
, A2a, Rs
, Adenosine A2a-receptor
, adenosine receptor A2a-like