General |
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Antigen | Chromogranin A (CHGA) Antikörper |
Reaktivität | Buffalo (Bubalus), Katze, Huhn, Rind (Kuh), Hund, Ente, Fisch, Meerschweinchen, Hamster, Pferd, Human, Affe, Maus, Ostrich (Struthio camelus), Schwein, Psittacula krameri, Ratte (Rattus), Schaf Alternativen |
Wirt | Kaninchen Alternativen |
Klonalität | |
Konjugat | Unkonjugiert Alternativen |
Applikation |
Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
Alternativen
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174 Publikationen vorhanden |
Hersteller | Anmelden zum Anzeigen |
ProduktdetailsAntigendetails Anwendungsinformationen Handhabung Referenzen Bilder |
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Kreuzreaktivität | Säugetier |
Produktmerkmale | The antibody has a proven strong staining at a 1/1000 - 1/2000 dilution in rat adrenal medulla using Biotin-Streptavidin/HRP detection method. |
Reinigung | Whole Serum |
Immunogen | SP-1 Chromogranin A |
Isotyp | IgG |
AntigendetailsProduktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben |
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Antigen | |
Andere Bezeichnung | Chromogranin A (CHGA Antibody Abstract) |
Hintergrund |
Other Names: Pituitary secretory protein I, CgA, chromogranin A (parathyroid secretory protein 1) |
Gen-ID | 281070 |
Pathways | Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling |
AnwendungsinformationenProduktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben |
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Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben |
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Format | Liquid |
Buffer | Contains ≤ 0.09 % sodium azide |
Konservierungs-mittel | Sodium azide |
Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Lagerung | 4 °C/-20 °C |
Informationen zur Lagerung | After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles. |
ReferenzenProduktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben |
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Produkt verwendet in: |
Leblanc, Langlois, Coulombe, Vaillancourt-Lavigueur, Jones, Carrier, Boudreau, Rivard: "Epithelial Src homology region 2 domain-containing phosphatase-1 restrains intestinal growth, secretory cell differentiation, and tumorigenesis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, pp. 3512-3526, 2017 Wang, Kwon, Singh, Islam, Liu, Sridhar, Hofmann, Browning: "Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium." in: Cell death and differentiation, Vol. 21, Issue 3, pp. 427-37, 2014 Reilly, Teo, Low, Amoyo-Brion, Dominguez-Brauer, Elia, Berger, Greicius, Pettersson, Mak: "Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression." in: Oncogene, Vol. 32, Issue 10, pp. 1233-9, 2013 Wolfs, Kallapur, Knox, Thuijls, Nitsos, Polglase, Collins, Kroon, Spierings, Shroyer, Newnham, Jobe, Kramer: "Antenatal ureaplasma infection impairs development of the fetal ovine gut in an IL-1-dependent manner." in: Mucosal immunology, Vol. 6, Issue 3, pp. 547-56, 2013 Rychel, Worley, Hardy, Webb: "Prolonged survival in an aged Labrador retriever with a metastatic insulinoma." in: Journal of the American Animal Hospital Association, Vol. 49, Issue 3, pp. 224-9, 2013 Ho, Sinha, Verzi, Bernt, Armstrong, Shivdasani: "DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions." in: Molecular and cellular biology, Vol. 33, Issue 9, pp. 1735-45, 2013 Gozalo, Zerfas, Starost, Lambert, Elkins: "Pancreatic endocrine tumour with disseminated pulmonary thromboembolism in an owl monkey (Aotus nancymae)." in: Journal of comparative pathology, Vol. 149, Issue 1, pp. 132-6, 2013 Gracz, Fuller, Wang, Li, Stelzner, Dunn, Martin, Magness: "Brief report: CD24 and CD44 mark human intestinal epithelial cell populations with characteristics of active and facultative stem cells." in: Stem cells (Dayton, Ohio), Vol. 31, Issue 9, pp. 2024-30, 2013 Dipaola, Shivakumar, Pfister, Walters, Sabla, Bezerra: "Identification of intramural epithelial networks linked to peribiliary glands that express progenitor cell markers and proliferate after injury in mice." in: Hepatology (Baltimore, Md.), Vol. 58, Issue 4, pp. 1486-96, 2013 Feng, Sentani, Wiese, Sands, Green, Bommer, Cho, Fearon: "Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation." in: The American journal of pathology, Vol. 183, Issue 2, pp. 493-503, 2013 Schaffer, Weishaar, Han: "Endobronchial metastasis in a dog with sarcoma." in: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, Vol. 25, Issue 4, pp. 546-50, 2013 Hu He, Juhl, Karadimos, El Khattabi, Fitzpatrick, Bonner-Weir, Sharma: "Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA." in: Developmental biology, Vol. 385, Issue 1, pp. 2-12, 2013 Grozinsky-Glasberg, Thomas, Strosberg, Pape, Felder, Tsolakis, Alexandraki, Fraenkel, Saiegh, Reissman, Kaltsas, Gross: "Metastatic type 1 gastric carcinoid: a real threat or just a myth?" in: World journal of gastroenterology : WJG, Vol. 19, Issue 46, pp. 8687-95, 2013 Gonzalez, Williamson, Piedrahita, Blikslager, Magness: "Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration." in: PLoS ONE, Vol. 8, Issue 6, pp. e66465, 2013 Roy, Langlois, Carrier, Boudreau, Rivard, Perreault: "Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes." in: World journal of gastroenterology : WJG, Vol. 18, Issue 14, pp. 1579-89, 2012 Wang, Kwon, Thangaraju, Singh, Liu, Jay, Hofmann, Ganapathy, Browning: "Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 303, Issue 2, pp. G209-19, 2012 Erlandsen, Qvigstad, Fossmark, Bakke, Chen, Sandvik: "Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach." in: Regulatory peptides, Vol. 177, Issue 1-3, pp. 53-9, 2012 Stauffer, Orentas, Lincoln, Khan, Salcedo, Hixon, Back, Wei, Patidar, Song, Hurd, Tsokos, Lai, Eisenhofer, Weiss, Khan, Wigginton: "High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery." in: Cancer investigation, Vol. 30, Issue 5, pp. 343-63, 2012 Li, Kapoor, Giel-Moloney, Rindi, Leiter: "Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine." in: Developmental biology, Vol. 371, Issue 2, pp. 156-69, 2012 Lu, Germano, Ohning, Vu, Pisegna: "PAC1 deficiency in a murine model induces gastric mucosa hypertrophy and higher basal gastric acid output." in: Journal of molecular neuroscience : MN, Vol. 43, Issue 1, pp. 76-84, 2011 |
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Bilder des Herstellers |
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Antigen | CHGA |
Chargennummer | 1436001 |
Validierte Anwendung | Immunohistochemistry |
Positivkontrolle | Macaque hippocampus sections |
Negativkontrolle | No primary antibody |
Bewertung |
Passed. ABIN617895 specifically labels the targeted antigen in macaque hippocampus in IHC. No signal was detected in sample negative control tissue and in the secondary antibody only control. |
Primärantikörper | ABIN617895 |
Sekundärantikörper | goat anti-rabbit IgG, biotin-conjugated antibody (Vector, BA-1000, lot W1002) |
Protokoll |
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Anmerkungen |
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