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Human Monoclonal IGFBPI Primary Antibody für ELISA, WB - ABIN259029
Logan, Ponnampalam, Rahnama, Lobie, Mitchell: The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells. in Human reproduction (Oxford, England) 2010
Human Polyclonal IGFBPI Primary Antibody für ELISA, WB - ABIN4321640
Sugita, Morishita, Kano, Furuya, Shiba-Ishii, Noguchi: IGFBP-1 is expressed specifically in ovarian clear cell adenocarcinoma. in Histopathology 2011
Human Polyclonal IGFBPI Primary Antibody für IHC, IHC (p) - ABIN4321641
Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014
hypoxia causes PGC (zeige PGC Antikörper) migration defect by inhibiting IGF signaling through the induction of IGFBP-1
The insulin-like growth factor binding protein 1 (29-31kDa)is similarities to mammalian.
HIF-1 (zeige HIF1A Antikörper) mediates hypoxia-induced IGFBP-1 gene expression in early development by selectively interacting with the hypoxia response elements and its adjacent HIF-1 (zeige HIF1A Antikörper) ancillary sequence.
TGE (zeige TGM3 Antikörper) duplicated IGFBP-1 may provide additional flexibility in fine-tuning insulin (zeige INS Antikörper)-like growth factor signaling activities under hypoxia and other catabolic conditions.
IGF2, IGF binding protein 1, and matrix metalloproteinases 2 and 9 in implantation-stage endometrium following immunoneutralization of vascular endothelial growth factor (zeige VEGF Antikörper) in the rhesus monkey.
These data support the hypothesis that down regulation of the insulin (zeige INS Antikörper)-like growth factor (IGF-I (zeige IGF1 Antikörper)) signaling links decidual phosphorylated insulin (zeige INS Antikörper)-like growth factor-binding protein (IGFBP-1) hyperphosphorylation to restricted fetal growth in placental insufficiency.
There was underexpression of the majority of genes after sunitinib treatment. The lower expression levels of IGFBP1, CCL20 (zeige CCL20 Antikörper), CXCL6 and FGB (zeige FGB Antikörper) were confirmed by qRT-PCR in all cases. The downregulation of gene expression leads us to search for methylation as a mechanism of action of the tyrosine kinase (zeige TXK Antikörper) inhibitors
A panel consisting of IGFBP1, KIM1 (zeige HAVCR1 Antikörper), GCLC (zeige GCLC Antikörper) and GSTM1 (zeige GSTM1 Antikörper) genes could be used in combination for early screening of CKDu, whereas these genes in addition with FN1 (zeige FN1 Antikörper), IGFBP3 (zeige IGFBP3 Antikörper) and KLK1 (zeige KLK1 Antikörper) could be used to monitor progression of CKDu. The regulation of these genes has to be studied on larger populations to validate their efficiency for further clinical use.
NR4A modulates the decidualization of hESCs by upregulating prolactin (PRL (zeige PRL Antikörper)) and insulin-like growth factor binding protein-1 (IGFBP-1) expression and transformation in vitro.
We report interactions between CSNK (zeige CSN3 Antikörper)-2beta and IGFBP-1 as well as mTOR (zeige FRAP1 Antikörper) and CSNK (zeige CSN3 Antikörper)-2beta, providing strong evidence of a mechanistic link between mTOR (zeige FRAP1 Antikörper) and IGF-I (zeige IGF1 Antikörper) signaling, two critical regulators of cell growth via CSNK (zeige CSN3 Antikörper)-2.
IGFBP-1 had a positive linear relation to fracture risk, partly mediated by bone mineral density (BMD (zeige BEST1 Antikörper)) but not related to IGF-I (zeige IGF1 Antikörper) or BMD (zeige BEST1 Antikörper)
We conclude that low BDNF (zeige BDNF Antikörper) and high LCN2 (zeige LCN2 Antikörper) and NF-L (zeige NEFL Antikörper) levels are associated with Multiple Sclerosis (MS) pathogenesis, and high IGFBP1level is a biomarker for female MS only, suggesting different MS progression pathways between the sexes. LCN2 (zeige LCN2 Antikörper) is a candidate predictor of response to natalizumab treatment, and NF-L (zeige NEFL Antikörper) is a candidate predictor of clinically isolated syndrome's (CIS (zeige CISH Antikörper)) conversion into MS.
Results show that IGFBP-1 transcription and FoxO1 (zeige FOXO1 Antikörper) expression are dysregulated in tamoxifen-resistant cancer cells.
Women with higher IGFBP-1 were more likely to have a low relative muscle mass.
Data show that supplementation with selenium and coenzyme Q10 (zeige EIF2C2 Antikörper) over four years resulted in increased levels of IGF-1 (zeige IGF1 Antikörper) and the postprandial IGFBP-1.
the hepatokine IGFBP1 is a critical liver-bone hormonal relay that promotes osteoclastogenesis and bone resorption as well as an essential mediator of FGF21 (zeige FGF21 Antikörper)-induced bone loss
Data suggest expression of Igfbp1 in liver is regulated by dietary factors; carnosine supplementation down-regulates expression of Igfbp1 in liver of obese/diabetic mice; mechanism involves suppression of Hif1a (hypoxia inducible factor 1 alpha (zeige HIF1A Antikörper)).
During the two week starvation period, both the levels of plasma IGF-1 (zeige IGF1 Antikörper) and IGFBP-1 decreased.
These results show that RTEF-1 (zeige TEAD4 Antikörper)-stimulated IGFBP-1 expression may be central to the mechanism by which RTEF-1 (zeige TEAD4 Antikörper) attenuates blood glucose levels.
Global deletion of Igfbp1 in a c-Myc (zeige MYC Antikörper) transgenic model did not accelerate the development of prostate cancer. Global Igfbp1 deletion did result in a significant increase in body weight and body fat mass.
IGFBP-1 functions as a critical hepatic survival factor in the liver by reducing the level of proapoptotic signals
IGFBP-1 may support liver regeneration at least in part via its effect on MAPK/ERK (zeige MAPK1 Antikörper) and C/EBP beta (zeige CEBPB Antikörper) activities. These findings are the first demonstration of the involvement of IGFBP-1 in the regulation of in vivo mitogenic signaling pathways.
Induction of IFGBP1 expression by amino acid deprivation of HepG2 hepatoma cells involves both a transcriptional activation and an mRNA stabilization due to its 3'UTR (zeige UTS2R Antikörper).
high concentrations of circulating IGFBP-1 are sufficient to cause fetal growth restriction in an animal model
the IGFBP-1 gene is a primary target of peroxisome proliferator-activated receptors
Allantoic fluid levels of IGFBP-1 were increased in nuclear transfer pregnancies
IGFBP1 is a common endometrial marker of conceptus elongation in sheep and cattle and most likely regulates conceptus elongation by stimulating migration and attachment of the trophectoderm
Results of fluorescence in situ and radiation hybrid (RH) mapping assigned this gene to porcine chromosome (SSC (zeige CYP11A1 Antikörper)) 18q24-qter.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
insulin-like growth factor binding protein 1
, insulin-like growth factor binding protein-1
, IGF-binding protein 1
, alpha-pregnancy-associated endometrial globulin
, amniotic fluid binding protein
, binding protein-25
, binding protein-26
, binding protein-28
, growth hormone independent-binding protein
, insulin-like growth factor-binding protein 1
, placental protein 12
, INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1)