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Results indicate that G protein beta2 (Gbeta2) is required for starvation-induced NF-kappaB activation and constitutive NF-kappaB activity.
G protein subunits beta1 and beta2 have different roles in neutrophil function, as revealed by gene expression silencing in primary mouse neutrophils
A GNB2 gene mutation is associated with familial sinus node and atrioventricular conduction dysfunction.
GNB1 and GNB2 alterations confer transformed and resistance phenotypes across a range of human tumors and may be targetable with inhibitors of G protein signaling.
MIF and GNbeta2 interacted with influenza A H1N1 virus PB1-F2 protein.
This protein has been found differentially expressed in the anterior cingulate cortex from patients with schizophrenia
We conclude that the Gbetagamma complex interacts with the GR and suppresses its transcriptional activity by associating with the transcriptional complex formed on GR-responsive promoters.
Recombinant Gbetagamma subunits were used to establish that the Gbeta(2)gamma(2) dimer can selectively reconstitute the inhibition of alpha(1H) channels in isolated membrane patches.
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR.
guanine nucleotide binding protein (G protein), beta polypeptide 2
, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2-like
, g protein subunit beta-2
, guanine nucleotide binding protein, beta 2
, guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
, guanine nucleotide-binding protein, beta-2 subunit
, transducin beta chain 2
, G protein, beta-2 subunit
, guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2
, signal-transducing guanine nucleotide-binding regulatory protein beta subunit
, guanine nucleotide binding protein (G protein),beta polypeptide 2
, guanine nucleotide binding protein (G protein), beta 2
, guanine nucleotide binding protein beta 2 subunit
, guanine nucleotide binding protein, beta polypeptide 2
, guanine nucleotide-binding protein, beta 2